Multi-scan heart MRI to study cardiovascular diseases in adults
Tests a combined heart MRI scan in adults with suspected or confirmed heart disease.
Plain-language title generated from the registry record
Registry title: Multimodal mAgnetic Resonance imaGIng in Cardiovascular Disease
Key facts
- Where
- Hangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with suspected or confirmed heart disease who need a heart MRI scan to find the cause or to look at the heart muscle.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Suspected or confirmed cardiovascular disease, such as ischemic heart disease, non-ischemic cardiomyopathy, myocarditis or valve disease.
Main reasons for not taking part
- Metal implants that are not MRI compatible, such as old pacemakers, ICDs or aneurysm clips
- Severe claustrophobia that prevents finishing the scan
- Severe renal insufficiency
- Pregnant or breastfeeding women
- Severe arrhythmia, such as persistent atrial fibrillation, that makes the MRI images too poor to use
Read by machine on 12 November 2026.
Where in China
- The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou, ChinaContact: jiaqi FanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Second Affiliated Hospital, Zhejiang University, School of Medicine
- Trial code
- NCT07617844
- Record updated
- 28 July 2026
- Original description
This single-center, prospective, observational cohort study aims to evaluate the clinical application value of multi-modal cardiovascular magnetic resonance (CMR) imaging in patients with cardiovascular diseases (CVD).Read full original descriptionShow less
Multimodal-MRI in Cardiovascular Diseases
This single-center, prospective, observational cohort study aims to evaluate the clinical application value of multi-modal cardiovascular magnetic resonance (CMR) imaging in patients with cardiovascular diseases (CVD).
While traditional imaging methods have limitations in fully evaluating myocardial tissue characteristics, multi-modal CMR offers a comprehensive, non-invasive "one-stop" assessment. It can simultaneously evaluate heart structure, function, tissue features (such as fibrosis and edema), and hemodynamics.
The study plans to enroll patients with suspected or confirmed CVD. Participants will undergo a comprehensive multi-modal CMR scan (including Cine, T1/T2 mapping, Late Gadolinium Enhancement, and 4D flow sequences) as part of their evaluation. In addition to clinical evaluation, the study will explore sequence optimization (e.g., comparing pre-contrast vs. post-contrast Cine, and 3-slice vs. 9-slice T1 mapping) and evaluate deep learning-based virtual native enhancement (VNE) models trained under different sequence protocols.
By tracking clinical outcomes, the study seeks to establish a standardized imaging assessment system to improve the early detection, accurate diagnosis, risk stratification, and prognostic prediction for various types of cardiovascular diseases.
Inclusion: Aged 18 years and older, with no gender restrictions; Clinically suspected or confirmed cardiovascular disease (including but not limited to ischemic heart disease, non-ischemic cardiomyopathy, myocarditis, valvular disease, etc.), requiring a cardiac magnetic resonance (CMR) examination to determine the etiology or evaluate myocardial tissue characteristics; No contraindications to magnetic resonance examination, and able to cooperate with breath-holding instructions; Voluntarily participate in this study and sign a written informed consent form.
Exclusion: Absolute contraindications: Implantation of non-MRI compatible metallic foreign bodies (e.g., old pacemakers, implantable cardioverter-defibrillators [ICD], aneurysm clips, etc.); Relative contraindications: Severe claustrophobia, unable to complete the examination despite communication; Severe renal insufficiency; Special populations: Pregnant or lactating women; Presence of severe arrhythmias (e.g., persistent atrial fibrillation) leading to severely impaired magnetic resonance signal acquisition, rendering the image quality inadequate for diagnosis; Poor expected compliance: Unable to complete follow-up, or deemed unsuitable for enrollment by the investigator for other reasons.