Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage
Key facts
- Where
- Rochester, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07619300, who can take part
Where in United States
- Mayo ClinicRochester, United StatesContact: Peter J. Grahn, Ph.D.No longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Peter J. Grahn, Ph.D.
- Trial code
- NCT07619300
- Record updated
- 15 September 2026
- Original description
The purpose of this study is to study sensorimotor circuit activity generated in response to temporarily implanted dorsal root ganglion stimulation by recording from muscles of the lower extremities as well as functional outcomes achieved over a 10-day rehabilitation program in an individual with lower motor neuron injury.Read full original descriptionShow less
Pilot Study: Dorsal Root Ganglion Stimulation After Spinal Cord Injury-Related Lower Motor Neuron Damage
The purpose of this study is to study sensorimotor circuit activity generated in response to temporarily implanted dorsal root ganglion stimulation by recording from muscles of the lower extremities as well as functional outcomes achieved over a 10-day rehabilitation program in an individual with lower motor neuron injury.
Inclusion: Traumatic and non-traumatic spinal cord injury (SCI); ASIA Impairment Scale (AIS) A-D; SCI below the tenth thoracic vertebral level; Greater than 1 year post-SCI; Intact spinal reflexes at or below injury level in 1 or more muscles.
Exclusion: Active, untreated urinary tract infection; Unhealed decubitus ulcer; Untreated clinical diagnosis of psychiatric disorder; Other implanted stimulation devices (e.g., deep brain stimulator, cardiac pacemaker, diaphragmatic pacer, etc.); History of clinically diagnosed cardiopulmonary disorder, such as severe orthostatic hypotension, which may impede participation in rehabilitation activities such as changes in body position such as supine-to-sit-to-stand activities, prolonged standing, or stepping; History of frequent and/or severe autonomic dysreflexia; History of seizure disorder; Any illness or condition which, based on the research team's assessment, will compromise with the patient's ability to comply with the protocol, patient safety, or the validity of the data collected during this study; Currently a prison inmate, or awaiting trial, related to criminal activity; Pregnancy at the time of screening for trial enrollment; Unhealed skeletal fracture; Spinal abnormality that may impede percutaneous implantation of spinal electrodes; Joint contractures that impede typical range of motion; Non-MRI-compatible implanted medical devices; Active participation in an interventional clinical trial which, based on the research team's assessment, may compromise protocol compliance, safety, and/or validity of data collected during this study.