Two Treadmill Exercise Styles in Cardiac Rehabilitation for Coronary Artery Disease
Compares two treadmill exercise styles in people with coronary artery disease during rehabilitation.
Plain-language title generated from the registry record
Registry title: High-Intensity Interval Training vs Moderate-Intensity Continuous Training in Phase II Cardiac Rehabilitation
Key facts
- Where
- Multan, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07619664, who can take part
Where in Pakistan
- Ch Pervaiz Elahi institute of cardiology Multan.Multan, PakistanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Riphah International University
- Trial code
- NCT07619664
- Record updated
- 2 June 2026
- Original description
This randomized controlled trial aims to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) in patients undergoing Phase II cardiac rehabilitation after coronary artery disease or post-angioplasty. A total of 66 participants will be randomly allocated into two groups: HIIT (n=33) and MICT (n=33). The intervention will be conducted 3 times per week using treadmill-based exercise protocols under heart rate monitoring. Primary outcomes include changes in left ventricular ejection fraction, functional capacity measured by 6-minute walk test, and lipid profile parameters before and after intervention. Secondary assessment includes health-related quality of life (HRQoL). The study aims to determine which exercise modality provides superior cardiovascular and functional improvement in stable cardiac patients during supervised rehabilitation.Read full original descriptionShow less
Effects of High-Intensity Interval Training vs Moderate-Intensity Continuous Training on Ejection Fraction, Functional Capacity, and Lipid Profiles in Phase II Cardiac Rehabilitation
This randomized controlled trial aims to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) in patients undergoing Phase II cardiac rehabilitation after coronary artery disease or post-angioplasty. A total of 66 participants will be randomly allocated into two groups: HIIT (n=33) and MICT (n=33). The intervention will be conducted 3 times per week using treadmill-based exercise protocols under heart rate monitoring. Primary outcomes include changes in left ventricular ejection fraction, functional capacity measured by 6-minute walk test, and lipid profile parameters before and after intervention. Secondary assessment includes health-related quality of life (HRQoL). The study aims to determine which exercise modality provides superior cardiovascular and functional improvement in stable cardiac patients during supervised rehabilitation.
Inclusion: Adults aged 18-60 years; Diagnosed with stable coronary artery disease confirmed by angiography, stress testing, or echocardiography; Left ventricular ejection fraction ≥45%; Functional NYHA Class I or II; Medically cleared by a cardiologist to participate in exercise (including recent ECG or stress test if necessary); Lightly active lifestyle prior to study (not involved in structured exercise programs).
Exclusion: Unstable angina or recent myocardial infarction (within the past 6 weeks); Uncontrolled hypertension (systolic BP >180 mmHg or diastolic BP >110 mmHg); Severe valvular heart disease, arrhythmias, or left ventricular dysfunction (EF <35%); Musculoskeletal disorders (e.g., severe osteoarthritis, recent fractures, or surgeries) preventing safe participation in exercise; Neurological disorders affecting mobility or safe exercise (e.g., stroke, Parkinson's disease); Any other condition judged by the investigator to make participation unsafe; Uncontrolled diabetes mellitus (HbA1c >9% or recent hypoglycemia).