Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment

Trial details

Who runs it

Xuanwu Hospital, Beijing

Trial code

NCT07620626

Record updated

11 June 2026

Original description

We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component. The study will include patients with IAs treated with commercially available WEB devices under the direction of treating physicians in routine clinical practice. Clinical, procedural, imaging, and safety data will be collected using a standardized electronic data capture system, with safety events adjudicated by an independent clinical events committee and imaging outcomes assessed by an independent core laboratory. The primary objective is to evaluate 12-month adequate aneurysm occlusion and major adverse events after WEB treatment. The study is expected to provide comprehensive post-market evidence on the real-world performance of the WEB device in China, including its safety, effectiveness, clinical appropriateness, and health economic value in routine neurointerventional practice.Read full original descriptionShow less

A Real-World Study of Intrasaccular Flow Disruption Devices for the Treatment of Intracranial Aneurysms

We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component. The study will include patients with IAs treated with commercially available WEB devices under the direction of treating physicians in routine clinical practice. Clinical, procedural, imaging, and safety data will be collected using a standardized electronic data capture system, with safety events adjudicated by an independent clinical events committee and imaging outcomes assessed by an independent core laboratory. The primary objective is to evaluate 12-month adequate aneurysm occlusion and major adverse events after WEB treatment. The study is expected to provide comprehensive post-market evidence on the real-world performance of the WEB device in China, including its safety, effectiveness, clinical appropriateness, and health economic value in routine neurointerventional practice.

Inclusion: Retrospective Cohort:; Participants of any age and sex; Patients treated for an intracranial aneurysm using a commercially available MicroVention Woven EndoBridge device; Patients who completed at least one postoperative imaging follow-up; Prospective Cohort:; Participants of any age and sex; Patients treated for an intracranial aneurysm using a commercially available MicroVention Woven EndoBridge device; The participant, or legally authorized representative if applicable, understands the study requirements and procedures and provides written informed consent before any study-specific data collection.

Exclusion: Patients treated with a Woven EndoBridge device for whom intraoperative or postoperative follow-up imaging data are not available; Patients with a life expectancy of less than 1 year due to other diseases or conditions; Retrospective Cohort:; Patients considered by the investigator to be unsuitable for participation in this study; Prospective Cohort:; Participants who are currently participating in, or plan to participate during the follow-up period, another clinical study that may affect the results of this study; Patients who are currently unable or expected to be unable to complete follow-up; Patients considered by the investigator to be unsuitable for participation in this study.

ClinicalTrials.gov NCT07620626