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Removing the fallopian tubes during gallbladder surgery to help prevent ovarian cancer

Tests removing the fallopian tubes during gallbladder removal surgery, to prevent ovarian cancer.

Plain-language title generated from the registry record
Registry title: Preventing Ovarian Cancer Through Opportunistic Salpingectomy at the Time of Laparoscopic Cholecystectomy

Key facts

Where
Hamilton, Langley, and Vancouver, CanadaSee the 3 sites

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people with fallopian tubes who are having their gallbladder removed by keyhole surgery. The fallopian tubes would be removed at the same time to lower ovarian cancer risk.

Age
35 years and older
Sex
Female (people with fallopian tubes)
Earlier treatment
Cannot have had a fallopian tube removal (salpingectomy) or tube and ovary removal before.

Main reasons for not taking part

  • Less than 24 hours between the surgeon consult and the surgery
  • Wish for a future pregnancy
  • Fallopian tubes already removed (salpingectomy or salpingo-oophorectomy)

Read by machine on 9 November 2026.

Where in Canada

  • Hamilton Health Sciences CenterHamilton, CanadaNo longer taking part
  • Langley Memorial HospitalLangley, CanadaNo longer taking part
  • Vancouver General Hospital (VGH)Vancouver, CanadaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University of British Columbia
Trial code
NCT07625137
Record updated
4 June 2026
Original description
This study aims to evaluate the feasibility, safety, and cost-effectiveness of opportunistic salpingectomy (OS-the removal of the fallopian tubes) at the time of laparoscopic cholecystectomy (the removal of the gallbladder) to prevent ovarian cancer. Ovarian cancer is the fifth leading cause of cancer-related mortality in females in Canada. OS can prevent the most common and lethal type of ovarian cancer, high-grade serous carcinoma (HGSC). OS during gynecologic surgery (hysterectomy or instead of tubal ligation) is safe and effective. However, rates of hysterectomies and tubal sterilization are decreasing. This research team aims to extend the prevention of ovarian cancer by expanding to offer OS during other surgeries in the abdomen, when patients are already undergoing a surgical procedure. This study will examine: 1) the feasibility of OS at the time of laparoscopic cholecystectomy; 2) the safety of OS at the time of laparoscopic cholecystectomy; 3) any health services consequences of offering OBS during laparoscopic cholecystectomy.Read full original descriptionShow less

Expanding Opportunistic Bilateral Salpingectomy to Laparoscopic Cholecystectomy to Prevent Ovarian Cancer: A Feasibility and Safety Trial

This study aims to evaluate the feasibility, safety, and cost-effectiveness of opportunistic salpingectomy (OS-the removal of the fallopian tubes) at the time of laparoscopic cholecystectomy (the removal of the gallbladder) to prevent ovarian cancer. Ovarian cancer is the fifth leading cause of cancer-related mortality in females in Canada. OS can prevent the most common and lethal type of ovarian cancer, high-grade serous carcinoma (HGSC). OS during gynecologic surgery (hysterectomy or instead of tubal ligation) is safe and effective. However, rates of hysterectomies and tubal sterilization are decreasing. This research team aims to extend the prevention of ovarian cancer by expanding to offer OS during other surgeries in the abdomen, when patients are already undergoing a surgical procedure. This study will examine: 1) the feasibility of OS at the time of laparoscopic cholecystectomy; 2) the safety of OS at the time of laparoscopic cholecystectomy; 3) any health services consequences of offering OBS during laparoscopic cholecystectomy.

The hypothesis is that OS at the time of laparoscopic cholecystectomy is a feasible, safe, and cost-effective primary prevention strategy for ovarian cancer. It is also hypothesized that there will be 10-20 minutes of additional operating room time for completing OS, and that integrating the identified partners and knowledge users, as well as adding relevant knowledge users as the project progresses, will affect the rapid mobilization of our findings.

Inclusion: Individuals with fallopian tubes who are undergoing lap chole and have more than 24 hours from surgeon consult to surgery, regardless of menopausal status; Age of 35 years and older; Patient must be able to give oral and written informed consent; Premenopausal patients will be included but will be counseled regarding their fertility.

Exclusion: Less than 24 hours available from surgeon consult to surgery; Previously had a salpingectomy or salpingo-oophorectomy; Individuals with a desire for a future pregnancy.

ClinicalTrials.gov NCT07625137