Tests ear nerve stimulation effects on brain blood flow and thinking after stroke
Tests ear-based vagus nerve stimulation in chronic stroke patients aged 50 to 60.
Plain-language title generated from the registry record
Registry title: Effect of Non-invasive Vagus Nerve Stimulation on Cerebrovascular Reactivity and Cognition in Chronic Stroke Patients
Key facts
- Where
- Cairo, EgyptSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 60 years old?
Source: NCT07626242, who can take part
Where in Egypt
- Ahmed Safwat KamalCairo, EgyptNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Cairo University
- Trial code
- NCT07626242
- Record updated
- 4 June 2026
- Original description
This study will be conducted to assess the effect of non-invasive vagus nerve stimulation on cerebrovascular reactivity and cognition in chronic stroke patientsRead full original descriptionShow less
Effect of Non-invasive Vagus Nerve Stimulation on Cerebrovascular Reactivity and Cognition in Chronic Stroke Patients
This study will be conducted to assess the effect of non-invasive vagus nerve stimulation on cerebrovascular reactivity and cognition in chronic stroke patients
Inclusion: Forty chronic ischemic hemiparetic patients, of both sexes, will represent the sample; The patient's age will range from 50 to 60 years old; Duration of illness will range from six months to twelve months; Patients with mild cognitive impairment according to Montreal Cognitive Assessment (MoCA) scale (from 18 to 25); Spasticity will be 1 or 1+ according to Modified Aschworth scale; Educated patients.
Exclusion: Patients with any taVNS contraindications (open heart surgery, pacemaker or other implants, previous surgical intervention on Vagus nerve, Facial or ear pain, and recent ear trauma); Patients with other neurological disease that affect cognition; History of psychiatric disease; Hemorrhagic stroke patients; Uncontrolled blood pressure or low heart rate; Stroke patients with severe cognitive impairment; Uncontrolled diabetes (>130 mg/dL especially if consistently over 150 to 160 mg/dL); The patients will be excluded if they have one of the followings:; Visual, verbal or hearing impairments that can interfere with communication; Depression assessed by Hamilton Depression Scale (Ham-D); Patients with poor bone window; Uncooperative patients.