Brain scans of connections and metabolism in people with glioblastoma
Adds extra MRI sequences to a PET scan in adults with glioblastoma.
Plain-language title generated from the registry record
Registry title: Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
Key facts
- Where
- Strasbourg, FranceSee the site
Where in France
- Institut public de cancérologie Strauss EuropeStrasbourg, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre Paul Strauss
- Trial code
- NCT07628257
- Record updated
- 4 June 2026
- Original description
The aim of this study is to determine whether the diffuse cerebral metabolic disturbances observed in glioblastoma are exclusively linked to the direct and indirect effects of tumor infiltration (particularly structural disconnection), or whether they also reflect a more global alteration of neurometabolic and neurovascular coupling mechanisms.Read full original descriptionShow less
Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of Diffusion Tensor Imaging (DTI) and Resting State Functional MRI (Rs-fMRI) to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
The aim of this study is to determine whether the diffuse cerebral metabolic disturbances observed in glioblastoma are exclusively linked to the direct and indirect effects of tumor infiltration (particularly structural disconnection), or whether they also reflect a more global alteration of neurometabolic and neurovascular coupling mechanisms.
This approach thus aims to better understand the pathophysiological basis of cognitive impairment in glioblastoma and to characterize the impact of the disease at the level of brain networks.
Inclusion: Adult patients; Patients with glioblastoma; Patients treated in the Nuclear Medicine \& Molecular Imaging Department of the Strauss Institute for PET/MRI scans for:; Preoperative metabolic evaluation of a brain-expanding lesion.
Exclusion: Contraindications to MRI; Minor or incapacitated adult; Patient deprived of liberty; Patient under legal guardianship; Patient unable to consent; Pregnant or breastfeeding woman.