Two Tube Feeding Methods to Prevent Pneumonia After Severe Ischemic Stroke
Compares feeding into the intestine with feeding into the stomach after severe stroke.
Plain-language title generated from the registry record
Registry title: Gastric Feeding for the Prevention of Stroke-Associated Pneumonia
Key facts
- Where
- Nanjing, ChinaSee the site
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a severe ischemic stroke who have swallowing problems and are not on a ventilator. It compares two ways of tube feeding to prevent pneumonia after stroke.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Severe ischemic stroke with an NIHSS score above 16 [15-16], within 72 hours of onset, and swallowing problems confirmed by a swallowing test (Kubota Water Swallowing Test grade 3 or higher, or aspiration risk confirmed by FEES/VFSS).
Main reasons for not taking part
- Pneumonia when admitted
- High risk of bleeding or tear in the gut, or a blocked gut
- Severe liver or kidney problems
- Advanced cancer
- Pregnancy or breastfeeding
Read by machine on 9 November 2026.
Where in China
- Jinling Hospital, Medical School of Nanjing University, NanjingNanjing, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Jinling Hospital, China
- Trial code
- NCT07630090
- Record updated
- 5 June 2026
- Original description
This randomized controlled trial aims to compare the effectiveness of early post-pyloric feeding versus gastric feeding in preventing SAP in patients with severe ischemic stroke. The main question to answer is whether post-pyloric feeding group is better than the gastric feeding group for preventing SAP.Read full original descriptionShow less
Comparing Early Post-pyloric Feeding Versus Gastric Feeding for the Prevention of Stroke-Associated Pneumonia in Patients With Severe Ischemic Stroke
This randomized controlled trial aims to compare the effectiveness of early post-pyloric feeding versus gastric feeding in preventing SAP in patients with severe ischemic stroke. The main question to answer is whether post-pyloric feeding group is better than the gastric feeding group for preventing SAP.
Inclusion: Age ≥ 18 years; Diagnosis of severe ischemic stroke, with NIHSS score > 16 [15-16]; Confirmed dysphagia via swallowing assessment (Kubota Water Swallowing Test ≥ grade 3, or confirmed aspiration risk by FEES/VFSS); Time from onset to enrollment ≤ 72 hours; Expected survival ≥ 7 days; Non-mechanically ventilated patients; Signed informed consent from patient or legal representative.
Exclusion: High risk of gastrointestinal bleeding or perforation; Advanced malignant tumor; Diagnosed with pneumonia upon admission; Intestinal obstruction or gastrointestinal obstruction; Severe liver or kidney dysfunction; Pregnancy or breastfeeding; Refusal to participate in the study.