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Not yet taking people in ChinaPhase 4

Two Tube Feeding Methods to Prevent Pneumonia After Severe Ischemic Stroke

Compares feeding into the intestine with feeding into the stomach after severe stroke.

Plain-language title generated from the registry record
Registry title: Gastric Feeding for the Prevention of Stroke-Associated Pneumonia

Key facts

Where
Nanjing, ChinaSee the site
Phase
Phase 4

Where in China

  • Jinling Hospital, Medical School of Nanjing University, NanjingNanjing, ChinaNo longer taking part

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Trial details

Who runs it
Jinling Hospital, China
Trial code
NCT07630090
Record updated
5 June 2026
Original description
This randomized controlled trial aims to compare the effectiveness of early post-pyloric feeding versus gastric feeding in preventing SAP in patients with severe ischemic stroke. The main question to answer is whether post-pyloric feeding group is better than the gastric feeding group for preventing SAP.Read full original descriptionShow less

Comparing Early Post-pyloric Feeding Versus Gastric Feeding for the Prevention of Stroke-Associated Pneumonia in Patients With Severe Ischemic Stroke

This randomized controlled trial aims to compare the effectiveness of early post-pyloric feeding versus gastric feeding in preventing SAP in patients with severe ischemic stroke. The main question to answer is whether post-pyloric feeding group is better than the gastric feeding group for preventing SAP.

Inclusion: Age ≥ 18 years; Diagnosis of severe ischemic stroke, with NIHSS score > 16 [15-16]; Confirmed dysphagia via swallowing assessment (Kubota Water Swallowing Test ≥ grade 3, or confirmed aspiration risk by FEES/VFSS); Time from onset to enrollment ≤ 72 hours; Expected survival ≥ 7 days; Non-mechanically ventilated patients; Signed informed consent from patient or legal representative.

Exclusion: High risk of gastrointestinal bleeding or perforation; Advanced malignant tumor; Diagnosed with pneumonia upon admission; Intestinal obstruction or gastrointestinal obstruction; Severe liver or kidney dysfunction; Pregnancy or breastfeeding; Refusal to participate in the study.

ClinicalTrials.gov NCT07630090