Magnetic brain stimulation to help arm and hand recovery long after a stroke
Tests kTMP, a gentle magnetic stimulation, with arm rehabilitation in adults disabled by stroke.
Plain-language title generated from the registry record
Registry title: kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
Key facts
- Where
- San Francisco, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07631078, who can take part
Where in United States
- UCSF Mission Bay- Sandler Neurosciences CenterSan Francisco, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Magnetic Tides
- Trial code
- NCT07631078
- Record updated
- 29 September 2026
- Original description
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.Read full original descriptionShow less
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
Inclusion: Adults aged 18-80 years who have a history of an ischemic or hemorrhagic stroke ≥ 12 m prior to enrollment; Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-50; Ability to communicate, understand, and give appropriate consent. Participants can follow two-step commands; Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive).
Exclusion: Botulinum toxin injections of the affected upper extremity within 3 months prior to onset of study; Absolute contraindications related to non-invasive brain stimulation, including:; 9a) History of seizures in the last 12 months while taking anti-epilepsy medication 9b) Presence of any metal implants in the head (excluding the mouth), such as cortical stimulators and DBS, clips, coils, shunts, stents or skull plates, cochlear implants 9c) Permanent eye liner or head tattoos 9d) Implanted electronics such as pacemakers, defibrillators, intrathecal baclofen pumps or vagus nerve stimulator 9e) History of experiencing a serious adverse event during a previous transcranial magnetic stimulation (TMS) session; Participants with moderate or severe cognitive impairment (MMSE < 18); Language impairment or behavioral disorder that interferes with their ability to adhere to the protocol or to provide informed consent; Individuals who have a serious uncontrolled medical condition, including but not limited to severe cardiovascular and cardiopulmonary disease; Participants with sensory deficits FMA-S < 6/12 (with proprioception < 4/8); Participants with severe apraxia (TULIA < 5); Pregnancy or plans to become pregnant during the study period; Severe spasticity of the affected upper limb (Modified Ashworth ≥ 4).