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Following Young People With Cancer in Lower-Income Countries Through Routine Treatment

Follows young people with cancer receiving usual care, to learn about treatment problems.

Key facts

Who runs it
Resonance, Inc.
Where
Cairo, EgyptSee the siteAlso in 4 other countries, 5 sites
Trial code
Registry title
CAYA Cancer Prospective Cohort Study
Status
Recruiting
People taking part
6,000 people, planned
Started
18 Sept 2026
Expected to end
11 Nov 2032
Type of study
Observational
Record updated
29 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children, adolescents and young adults up to 21 years old who have cancer and are being treated or followed up at the study hospitals. It only follows routine care.

Age
0 to 21 years at enrolment.
Sex
All sexes can join.
Disease stage
Any cancer, in active treatment or in follow-up at the participating sites.
Earlier treatment
Patients seen only for consultation or diagnosis without later treatment, or off treatment for more than 5 years and seen only for survivorship follow-up, cannot join.

Main reasons for not taking part

  • Seen only for consultation or diagnostic tests, with no treatment afterwards
  • Off treatment for more than 5 years and seen only for survivorship follow-up
  • A medical or psychological condition that, in the investigator's opinion, could make it hard to give consent or assent

The registry criteria, word for word

Show all 6 criteriaShow less

Who can take part

  • Subjects must meet all the following criteria to be included in this study:
  • Age 0 to 21 years at study enrollment
  • Diagnosed with cancer and receiving active treatment or undergoing follow-up at the participating sites; Note: Patients seen solely for consultation or diagnostic evaluations without subsequent treatment and those who have been off treatment for more than 5 years and are seen only for survivorship follow-up are not considered as meeting this criterion
  • Willingness to provide informed consent/assent. For minors incapable of providing assent, or individuals unable to provide consent, consent must be obtained from a legal representative and in accordance with local requirements

Who cannot take part

  • Any medical or psychological condition that, in the investigator's opinion, might compromise the ability of the patient to provide assent/informed consent/assent
  • Subjects meeting any of the following criteria must be excluded from this study:

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 0 and 21 years old?

Where in Egypt

Also in 4 other countries, 5 sites

  • The Children's Cancer Hospital Egypt 57357Cairo, EgyptContact: Iman Sidhom, MD.Not yet recruiting

About the trial

What the trial wants to find out

Cancer is a leading cause of illness and death among children, adolescents, and young adults(CAYAs), especially in low- and middle-income countries(LMICs), where access to timely diagnosis and treatment is often limited. As a result, patients in these settings may experience higher rates of treatment complications, interruptions, and poorer outcomes compared with those in high-income countries (HICs).

Read full original descriptionShow less

This is a prospective, multicenter observational study that will follow children, adolescents, and young adults(CAYAs) with cancer who are receiving routine care at participating hospitals in low - and middle - income countries(LMICs). The study does not involve experimental treatments or changes to standard medical care. Information will be collected from medical records and from questionnaires that address access to care and social factors affecting treatment.

By describing treatment outcomes and the challenges patients and families face during cancer care, this study aims to provide data that can help inform future efforts to improve access to care and cancer outcomes in resource-limited settings.

The group in the trial

  • Children, Adolescents, and Young Adults With Cancer

    Participants include children, adolescents and young adults with a diagnosis of cancer who are receiving routine care at participating hospitals in low- and middle-income countries(LMIC). This study follows patients as part of a single observational cohort and does not assign any experimental treatments. All medical care is provided according to local standard practice. Participants are followed over time to document clinical outcomes, as well as factors related to access to care and the overall treatment experience.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Improving Cancer Outcomes for Children, Adolescents, and Young Adults: A Multicenter Prospective Cohort Study on Treatment Failure and Toxicity in Low- and Middle-Income Countries.
Plain-language title
Following Young People With Cancer in Lower-Income Countries Through Routine TreatmentGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Fit questions
Built from NCT07632014, who can take part
Record updated
29 September 2026