Tests lying face down after heart surgery on heart pumping function
Tests whether lying face down affects heart pumping in adults after cardiac surgery.
Plain-language title generated from the registry record
Registry title: Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Key facts
- Where
- Gothenburg, SwedenSee the site
Where in Sweden
- Cardiothoracic Intensive Care UnitGothenburg, SwedenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sahlgrenska University Hospital
- Trial code
- NCT07632027
- Record updated
- 23 October 2026
- Original description
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay. The right ventricle is particularly vulnerable to an increased afterload. By increasing pulmonary vascular resistance (PVR), atelectasis might mitigate a negative effect on the right ventricle.Read full original descriptionShow less
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine (the BAROLO Study) Hemodynamic Changes Due to Prone Position in Patients After Cardiac Surgery - a Prospective Randomized Controlled Trial Evaluating the Effect of Prone Position on Right Heart Function
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay. The right ventricle is particularly vulnerable to an increased afterload. By increasing pulmonary vascular resistance (PVR), atelectasis might mitigate a negative effect on the right ventricle.
Recruitment maneuvers have been shown to resolve atelectasis and improve hemodynamics by increasing cardiac output and lowering PVR. However these maneuvers transiently raise airway pressures, which in turn increases right ventricular afterload, a situation often poorly tolerated by patients with RVF.
Prone position is used in patients with respiratory failure and has been shown to decrease mortality in patients with ARDS. Prone position decreases atelectasis and moves ventilation dorsally. In ARDS it also seems to mediate beneficial hemodynamic effects such as an increase in cardiac output and a decrease in PVR.
The investigators hypothesis is that prone position early after cardiac surgery will increase cardiac output by recruitment of atelectasis and thereby decrease PVR.
Inclusion: Scheduled for cardiac surgery using cardiopulmonary bypass.
Exclusion: Emergency surgery; Severe pulmonary disease; Any condition which, in the judgement of the investigator, might increase the risk to the patient; BMI >40; Haemodynamic instability requiring Norepinephrine >0.5mcg/kg/min; Intracardiac shunt; Severe (or worse) tricuspid regurgitation.