A simpler deep sedation approach for pulsed-field ablation in atrial fibrillation
Looks at a simpler sedation method during ablation for adults with atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Safety And FEasibility of a Simplified Deep Sedation Protocol for Pulsed-Field Ablation
Key facts
- Where
- Caen, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07633548, who can take part
Where in France
- University Hospital CenterCaen, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Caen
- Trial code
- NCT07633548
- Record updated
- 8 June 2026
- Original description
The aim of the SAFE-PFA study is to demonstrate the feasibility and safety of a simplified deep-sedation protocol for pulsed-field ablation of atrial fibrillation, with a specific focus on patient-reported outcomes.Read full original descriptionShow less
Safety And FEasibility of a Simplified Deep Sedation Protocol for Pulsed-Field Ablation
The aim of the SAFE-PFA study is to demonstrate the feasibility and safety of a simplified deep-sedation protocol for pulsed-field ablation of atrial fibrillation, with a specific focus on patient-reported outcomes.
Inclusion: elective PFA-based AF catheter ablation.
Exclusion: Obstructive sleep apnea syndrome, treated or untreated; Chronic obstructive pulmonary disease or baseline SpO₂ < 95%; Cognitive impairment and/or psychiatric disorders; Heart failure classified as NYHA III or IV, or left ventricular ejection fraction < 40%; Obesity with BMI > 35 kg/m².