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Tests a nerve block for persistent back pain in ankylosing spondylitis

Tests an erector spinae plane block for ongoing back pain in adults with ankylosing spondylitis.

Plain-language title generated from the registry record
Registry title: Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis

Key facts

Where
Istanbul, TürkiyeSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with ankylosing spondylitis whose disease is controlled by treatment but who still have persistent back pain.

Age
18 to 65 years
Sex
All sexes can join.
Disease stage
Ankylosing spondylitis diagnosed by the Modified New York Criteria, with disease activity controlled under treatment and persistent back pain.
Earlier treatment
People must be on ongoing treatment for ankylosing spondylitis.

Main reasons for not taking part

  • Body mass index (BMI) greater than 35 kg/m²
  • History of thoracic surgery
  • Pregnancy
  • Active infection, local or systemic
  • Active phase of the disease (elevated acute phase reactants, active arthritis findings)

Read by machine on 13 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07633730, who can take part

Where in Türkiye

  • Marmara University Faculty of Medicine Pendik Training and Research HospitalIstanbul, TürkiyeContact: Fatma B Akdağ, Research AssistantTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Marmara University
Trial code
NCT07633730
Record updated
8 June 2026
Original description
Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing spondylitis. Although the erector spinae plane block has been described in the literature as a safe and effective analgesic intervention for chronic back pain in various patient populations, to the best of our knowledge, no clinical study has specifically evaluated its use for persistent back pain in patients with ankylosing spondylitis receiving medical treatment. Therefore, the present study aims to evaluate the effects of erector spinae plane block on pain severity and clinical outcomes in patients with ankylosing spondylitis whose disease activity is controlled under treatment but who continue to experience persistent back pain.Read full original descriptionShow less

Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis

Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing spondylitis. Although the erector spinae plane block has been described in the literature as a safe and effective analgesic intervention for chronic back pain in various patient populations, to the best of our knowledge, no clinical study has specifically evaluated its use for persistent back pain in patients with ankylosing spondylitis receiving medical treatment. Therefore, the present study aims to evaluate the effects of erector spinae plane block on pain severity and clinical outcomes in patients with ankylosing spondylitis whose disease activity is controlled under treatment but who continue to experience persistent back pain.

Inclusion: Age between 18 and 65 years; Diagnosis of ankylosing spondylitis according to the Modified New York Criteria; Patients receiving ongoing treatment with controlled disease activity but persistent back pain; Willingness to participate in the study.

Exclusion: History of thoracic surgery; Presence of major psychiatric comorbidity; History of bleeding diathesis; Presence of active local and/or systemic infection; Known allergy to the medications to be injected; Active phase of the disease (elevated acute phase reactants, active arthritis findings, etc.); Body mass index (BMI) greater than 35 kg/m²; Intellectual disability or mental retardation; Congenital spinal anomaly; Pregnancy; Hemodynamic instability.

ClinicalTrials.gov NCT07633730