Not yet taking people in TürkiyeNo phase

Exercise Interventions in Obstructive Sleep Apnea Syndrome

Key facts

Who runs it: Istanbul University - Cerrahpasa
Where: Istanbul, TürkiyeSee the site
Trial code: NCT07634029
Status: Not yet recruiting
People taking part: 39 people, planned
Started: 1 Sept 2026
Expected to end: Feb 2028
Type of study: Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested: Aerobic Exercise Training
Exercise Snacking
Record updated: 8 June 2026

Who can take part

Age: 30 years to 65 years
Sex: Women and men
Healthy volunteers: Cannot take part

The registry criteria, word for word

Show all 14 criteriaShow less

Who can take part

Individuals diagnosed with OSAHS (AHI ≥ 15) confirmed by polysomnography, with moderate or severe disease, who have been receiving CPAP therapy for at least 3 months
Adults aged 30-65 years
No participation in any regular exercise program within the last 6 months

Who cannot take part

Use of steroid or hormone therapy
Use of melatonin or sleep-regulating medications within the last 3 months
Severe chronic pulmonary disease
Neurological or musculoskeletal disorders that prevent exercise
Unstable cardiovascular conditions
Unstable metabolic conditions
Severe psychiatric disorders such as bipolar disorder or schizophrenia
Presence of acute infection or inflammation
Individuals with OSAHS and a body mass index (BMI) > 35 kg/m²
Pregnancy or breastfeeding
Individuals working night shifts or with schedules that may cause jet lag

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

Are you between 30 and 65 years old?

Where in Türkiye

Istanbul University-Cerrahpaşa, Department of Physiotherapy and Rehabilitation, Istanbul, TürkiyeIstanbul, TürkiyeContact: Melis UsulNo longer taking part

About the trial

What the trial wants to find out

Obstructive Sleep Apnea Syndrome (OSA) is a condition characterized by repeated pauses or reductions in breathing during sleep, which can negatively affect sleep quality, daytime functioning, and physical capacity. Although regular exercise is known to have beneficial effects in OSA, the effects of different exercise approaches on circadian rhythm and functional capacity have not been sufficiently investigated.The primary aim of this study is to compare the effects of exercise snacking and aerobic exercise on circadian rhythm and functional capacity in individuals with OSA, in comparison with a control group. The secondary aim is to evaluate the effects of these exercise interventions on peripheral muscle strength, fatigue level, body composition, quality of life, and physical activity level.Participants will be randomly assigned to three groups: an aerobic exercise group, an exercise snacking group, and a control group. While the exercise groups will follow their respective intervention programs, the control group will continue their routine treatment.This study aims to answer whether exercise snacking, which consists of short bouts of exercise distributed throughout the day, may be an alternative or complementary approach to traditional aerobic exercise in individuals with OSA. In addition, this study aims to be the first randomized controlled trial evaluating the effects of exercise snacking on circadian rhythm and functional capacity in individuals with OSA.

The 3 groups in the trial

Aerobic Exercise GroupExisting treatment, for comparison
Aerobic Exercise Training
Treatment: Aerobic Exercise Training
Exercise Snacks GroupTreatment being tested
Exercise Snacking
Treatment: Exercise Snacking
Control Group (Usual Care)No study treatment, for comparison
Usual Care