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Not yet taking people in PakistanPhase 4

Tapinarof cream compared with betamethasone cream for plaque psoriasis

Compares tapinarof cream with betamethasone cream in adults with mild to moderate plaque psoriasis.

Plain-language title generated from the registry record
Registry title: Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis

Key facts

Where
Islamabad, PakistanSee the site
Phase
Phase 4

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT07635043, who can take part

Where in Pakistan

  • Pakistan institute of medical sciences(PIMS)Islamabad, PakistanNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Pakistan Institute of Medical Sciences
Trial code
NCT07635043
Record updated
9 June 2026
Original description
To assess the effectiveness of topical tapinarof to topical betamethasone in patients with mild to moderate plaque psoriasis presenting to tertiary care hospital in IslamabadRead full original descriptionShow less

Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis

To assess the effectiveness of topical tapinarof to topical betamethasone in patients with mild to moderate plaque psoriasis presenting to tertiary care hospital in Islamabad

Inclusion: Age 18 years-65 years; Clinically diagnosed plaque psoriasis involving body surface area ( BSA) of 2-20% (mild to moderate severity); Disease duration of at least 6 months; Willing and able to provide written informed consent; Not currently using any other topical and systematic psoriasis therapy, or willing to undergo a washout period (2 weeks for topical therapies).

Exclusion: Severe psoriasis (BSA >20% or requiring systemic therapy); Concurrent dermatological conditions that may interfere with assessment e.g fungal infections,atopic dermatitis; Use of systemic immunosuppressants (methotrexate, cyclosporine, biologics ) or phototherapy within 4 weeks before enrollment; Use of powerful topical corticosteroids within two weeks previously; Known hypersensitivity to Tapinarof or any of its excipients; History of malignancy or current active infection; Known hypersensitivity to betamethasone or Tapinarof; Pregnant and lactating mothers.

ClinicalTrials.gov NCT07635043

Under construction, not live – Efficacy of Topical Tapinarof Versus Betamethasone in the Treatment of Plaque Psoriasis (NCT07635043) – Frontlight Research