Eccentric Muscle Training for People With Heart Failure in Cardiac Rehabilitation
Tests muscle-lengthening exercise against usual workouts in people with weakened heart pumping.
Plain-language title generated from the registry record
Registry title: Eccentric Muscle Training in Cardiac Rehabilitation
Key facts
- Where
- Edegem, BelgiumSee the site
Where in Belgium
- UHAntwerpEdegem, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Antwerp
- Trial code
- NCT07636343
- Record updated
- 9 June 2026
- Original description
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.Read full original descriptionShow less
Eccentric Muscle Training in Cardiac Rehabilitation: Randomized Controlled Trial to Evaluate Effectiveness and Feasibility in Heart Failure Patients With Reduced Ejection Fraction
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.
Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction.
This study will be delivered in a cardiac rehabilitation setting.
Inclusion: HFrEF patients with ejection fraction <40%; Exercise intolerance (<85% of predicted VO2 peak); clinically stable for > 6 weeks, optimal medical treatment for > 6 weeks.
Exclusion: Contra indications for cardiac exercise rehabilitation as per consensus guidelines and recommendations; Musculoskeletal disorders that hamper (progression in) strength training; Non-stabilized acute coronary syndrome; Current acute heart failure (decompensation); Patient having sustained a recent (<3 months) procedure that could act as a confounder to increase VO2peak (i.e., coronary artery bypass graft surgery, percutaneous coronary intervention, cardiac resynchronization therapy, valve surgery or reparation).