Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07636681, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Baghdad
- Trial code
- NCT07636681
- Record updated
- 9 June 2026
- Original description
1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism. 2. To assess the effect of a medication adherence-based digital intervention on weight in patients with hypothyroidism. 3. To investigate the effect of a medication adherence-based digital intervention on thyroid hormone regulation in patients with hypothyroidism.Read full original descriptionShow less
Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation in Patients With Hypothyroidism: A Randomized Controlled Trial
1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism. 2. To assess the effect of a medication adherence-based digital intervention on weight in patients with hypothyroidism. 3. To investigate the effect of a medication adherence-based digital intervention on thyroid hormone regulation in patients with hypothyroidism.
Inclusion: Adults (≥18 years) with primary hypothyroidism; On stable levothyroxine therapy for at least 3 months; Able to read, understand study instructions; capable of using basic mobile applications; poor medication adherence, clinically significant fatigue, documented weight fluctuations and abnormal thyroid hormone.
Exclusion: Secondary hypothyroidism or recent thyroidectomy/radioactive iodine therapy; take dietary supplements or medications that interfere with levothyroxine absorption; Severe psychiatric disorders or cognitive impairment; Serious comorbidities affecting medication adherence (e.g., chronic disease, renal, or hepatic disease); Pregnancy or breastfeeding woman; significant visual or hearing deficits.