NCT07640256CompletedPhase 4
Pain Management During Panretinal Photocoagulation for Diabetic Retinopathy: Safety and Efficacy of Peribulbar Anesthesia
Safety and Efficacy of Peribulbar Anesthesia for Pain Management in Patients With Proliferative Diabetic Retinopathy During Panretinal Photocoagulation
Source: ClinicalTrials.gov · Last updated 14 Jul 2026
Brief summary (registry, in English)
The purpose of this study was to compare two different anesthesia methods for pain control during panretinal photocoagulation (PRP), a type of laser surgery that treats proliferative diabetic retinopathy (PDR). The study included eyes from patients with diabetes and proliferative diabetic retinopathy who were scheduled to undergo their first PRP session. Participants were split into two groups to receive either peribulbar anesthesia, which is a type of anesthesia injected through the eyelid, or a sham injection with topical anesthesia only. Pain on a numerical scale and vital signs were recorded before and for 15 minutes during PRP. These results were compared between the two groups to determine which method delivers superior pain control.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 1 Jun 2026
- Start date
- 6 Jul 2023
- Primary completion date
- 21 Mar 2024
- Lead sponsor
- Asociación para Evitar la Ceguera en México
- Diseases
- Diabetic eye disease
- NCT number
- NCT07640256
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 50
- From 6 Jul 2023 to the primary completion date, 21 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of analgesics within 24 hours prior to treatment
Other illness
- History of phobic anxiety disorder related to needles or injections
- Known allergies or hypersensitivity to lidocaine, bupivacaine, or tetracaine
Other
- Cognitive or motor impairments that could hinder effective communication of pain.
Who the study is looking for
- Adults aged 18 years or older with proliferative diabetic retinopathy
- Scheduled to undergo their first PRP session
- Able to maintain the required posture at the slit lamp throughout the procedure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Asociacion Para Evitar la Ceguera en Mexico, I.A.P. Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.