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Studies heart rhythm problems in people with chronic kidney disease

Observes heart rhythm problems in adults with chronic kidney disease, with or without dialysis.

Plain-language title generated from the registry record
Registry title: Patterns of Cardiac Arrhythmia in Patients With Chronic Kidney Disease

Key facts

Where
Sohag, EgyptSee the site

Where in Egypt

  • Sohag university hospitalsSohag, EgyptNo longer taking part

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Trial details

Who runs it
Sohag University
Trial code
NCT07640919
Record updated
11 June 2026
Original description
Cardiovascular diseases remain the primary leading cause of death in patients on maintenance hemodialysis accounting for nearly 41% of deaths.Read full original descriptionShow less

Patterns of Cardiac Arrhythmia In Patients With Chronic Kidney Disease at Sohag University Hospitals

Cardiovascular diseases remain the primary leading cause of death in patients on maintenance hemodialysis accounting for nearly 41% of deaths.

Chronic kidney disease is associated with an excess of acquired arrhythmia of multiple types, and atrial fibrillation in particular.

Sudden cardiac death is also more common in chronic kidney disease and accounts for around one- quarter of deaths in dialysis patients.

The aim of the study is to evaluate the incidence, describe the patterns of cardiac arrhythmia and to determine the factors predisposing to cardiac arrhythmia in patients with chronic kidney disease with or without hemodialysis.

Inclusion: Patients with CKD (no intercurrent illness or uremic symptoms, and not hospitalized in the previous 3 months) with renal replacement therapy on maintenance HD (three times/week for at least three months) or without renal replacement therapy, aged 18 or above.

Exclusion: Patients with structural heart diseases (e.g.,significant valvular lesions ); Patients with malignancy, severe infection or sepsis; Patients with major bleeding; Patients on drugs that are known to prolong the QT interval (e.g., antibiotics as clarithromycin, antifungal as fluconazole, antiarrhythmics as amiodarone, antipsychotic as chlorpromazine); Patients aged <18 years old; Patients with impaired left ventricular systolic functions (defined as EF< 50%.

ClinicalTrials.gov NCT07640919