Blood sugar, gut lining and stomach symptoms after sleeve gastrectomy for severe obesity
Follows adults for 6 months after sleeve gastrectomy to check metabolism and gut health.
Plain-language title generated from the registry record
Registry title: Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management
Key facts
- Where
- Bursa, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 19-50 who had sleeve gastrectomy weight-loss surgery within the last month. They will be followed for 6 months.
- Age
- 19 to 50 years
- Sex
- All sexes can join.
- Disease stage
- Obesity: BMI of 40 kg/m² or more, or BMI of 35 kg/m² or more with obesity-related health problems.
- Earlier treatment
- Must have had Laparoscopic Sleeve Gastrectomy (LSG) within the last 1 month.
Main reasons for not taking part
- Smoker or alcohol dependent
- Has an inflammatory disease
- Currently using probiotics, antibiotics or fiber supplements
- Has a psychiatric disorder
- BMI below 40 kg/m², or below 35 kg/m² without obesity-related health problems
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 19 and 50 years old?
Source: NCT07643376, who can take part
Where in Türkiye
- Bursa Yıldırım Doruk HospitalBursa, TürkiyeContact: Doğukan DURAK;, Assoc. Prof.No longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Toros University
- Trial code
- NCT07643376
- Record updated
- 11 June 2026
- Original description
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity treatment.Read full original descriptionShow less
Evaluation of Postoperative Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms in Body Weight Management After Laparoscopic Sleeve Gastrectomy
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity treatment.
Obesity is a chronic disease associated with serious health complications including type 2 diabetes, hypertension, cardiovascular disease, and metabolic disorders. Bariatric surgery is currently the most effective treatment method for morbid obesity. However, monitoring patients after surgery in terms of metabolic health, gut permeability, and gastrointestinal symptoms is crucial for long-term success.
In this study, 40 volunteers (aged 19-50) who have undergone LSG surgery within the last month will be followed for 6 months. At the beginning of the study and 6 months later, the following will be assessed:
* Metabolic parameters: fasting blood glucose, total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL) cholesterol, and insulin levels * Intestinal permeability markers: zonulin, secretory immunoglobulin A (IgA), and lipopolysaccharide (LPS) levels * Gastrointestinal symptoms: assessed using the Gastrointestinal Symptom Rating Scale (GSRS) * Anthropometric measurements: body weight, height, waist and hip circumference, BMI * Nutritional intake: 3-day dietary records
The study will be conducted at Bursa Yıldırım Doruk Hospital, General Surgery Clinic. Results will contribute to understanding the relationship between bariatric surgery and gut health, potentially helping to prevent postoperative complications.
Inclusion: Underwent Laparoscopic Sleeve Gastrectomy (LSG) within the last 1 month; Aged between 19-50 years; BMI ≥40 kg/m² or BMI ≥35 kg/m² with obesity-related comorbidities; Signed informed consent form; Non-smoker and non-alcohol dependent.
Exclusion: Currently using probiotics, antibiotics, or fiber supplements; Has an inflammatory disease; Has a psychiatric disorder; Outside the age range of 19-50 years; Did not undergo or is not planned to undergo LSG; Did not sign the informed consent form; BMI <40 kg/m² or BMI <35 kg/m² without obesity-related comorbidities; Smoker or alcohol dependent.