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Rhythm Psychophysics With Parkinson's Patients

Key facts

Where
Hamilton, CanadaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 80 years old?

Source: NCT07647913, who can take part

Where in Canada

  • Psychology BuildingHamilton, CanadaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
McMaster University
Trial code
NCT07647913
Record updated
15 June 2026
Original description
The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:Read full original descriptionShow less

The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:

* Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information? * Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information? * Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information?

Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.

Inclusion: Parkinson's Disease diagnostic; Stage 1 or 2 Hoenh-Yahr scale; Taking immediate-release Levodopa; MoCA score of 26 or above.

Exclusion: Dementia; Other neurodegenerative disease; History of substance abuse; History of hearing disorders; History of neuropsychiatric disease.

ClinicalTrials.gov NCT07647913