Calcium and Vitamin D for Bone Health in Pregnant Women With Epilepsy
Tests daily calcium and vitamin D in pregnant women with epilepsy.
Plain-language title generated from the registry record
Registry title: Bone Management in Pregnancy Outcomes in Epilepsy
Key facts
- Where
- Zhejiang, ChinaSee the site
Where in China
- The Fourth Affiliated Hospital of Zhejiang University School of MedicineZhejiang, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
- Trial code
- NCT07651709
- Record updated
- 16 June 2026
- Original description
This study is aimed to evaluate the efficacy of bone health management in improving pregnancy outcomes among WWE, and establish evidence-based vitamin D supplementation strategies for childbearing-age WWE.Read full original descriptionShow less
Bone Health Management on Pregnancy Outcomes in Women With Epilepsy: Randomized Study
This study is aimed to evaluate the efficacy of bone health management in improving pregnancy outcomes among WWE, and establish evidence-based vitamin D supplementation strategies for childbearing-age WWE.
Inclusion: Diagnosis of focal or generalized epilepsy as defined by the International League Against Epilepsy; Women of childbearing age, aged ≥18 years, planning pregnancy or in early pregnancy (≤16 weeks gestation, confirmed by last menstrual period or ultrasound) - single pregnancy; Willing and able to provide written informed consent.
Exclusion: Recent/current use of bone-modifying drugs: bisphosphonates, glucocorticoids (≥5 mg/day prednisone equivalent for >1 month), or loop diuretics within the past year; Presence of other severe systemic diseases deemed unsuitable for study participation by the investigator; Pre-existing conditions affecting bone metabolism: primary hyperparathyroidism, Paget's disease, multiple myeloma, chronic kidney disease (eGFR <60 mL/min), cirrhosis (Child-Pugh B/C), or untreated hyper/hypothyroidism; History of metabolic complications: hypercalcemia (serum Ca²⁺ >10.5 mg/dL), nephrolithiasis, or granulomatous diseases; Ultrasound shows fetal malformation.