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Taking people in CanadaNo phase

Infant RSV Immunity Study

Key facts

Where
Vancouver, CanadaSee the site

Where in Canada

  • BC Women's Hospital and Health CentreVancouver, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of British Columbia
Trial code
NCT07653347
Record updated
17 June 2026
Original description
Respiratory Syncytial Virus (RSV) is a main global cause of respiratory illness and death in infants. Previous infant vaccine trials have failed to demonstrate protection. Moreover, RSV infection during early infancy, particularly in infants younger than 4 months of age, is associated with more severe disease, reduced immune protection, and an increased risk of developing childhood asthma. This study aim to investigate the immunological and long-term health effects of a first exposure to RSV early (<4 months) versus late (>6-9 months) in infancy.Read full original descriptionShow less

Understanding the Impact of Early-life RSV Infections on Infant Immunity and Long-term Health

Respiratory Syncytial Virus (RSV) is a main global cause of respiratory illness and death in infants. Previous infant vaccine trials have failed to demonstrate protection. Moreover, RSV infection during early infancy, particularly in infants younger than 4 months of age, is associated with more severe disease, reduced immune protection, and an increased risk of developing childhood asthma. This study aim to investigate the immunological and long-term health effects of a first exposure to RSV early (<4 months) versus late (>6-9 months) in infancy.

Inclusion: Birthing parent/child pairs with a delivery date in April, May or June or September, October or November who delivered or are planning to deliver at BC Women's Hospital + Health Centre or a nearby, local hospital.

Exclusion: Severe pregnancy-related complications or chronic medical conditions in the children making them automatically eligible to receiving RSV immunoprophylaxis in British Columbia (e.g. infants born prematurely < 35 weeks of gestation, or with chronic medical conditions).

ClinicalTrials.gov NCT07653347