NCT07653984Recruiting
Cohort Study on Neuroimmune Diseases in the Reproductive Age
Source: ClinicalTrials.gov · Last updated 17 Jun 2026
Brief summary (registry, in English)
Neuroimmune diseases are more prevalent among women of reproductive age. Studies have shown that neuroimmune diseases may impact fertility. Therefore, effective management of neuroimmune diseases during pregnancy is particularly important. This study included a follow-up period of up to five years in patients with pregnancy-associated neuroimmune disorders. Data collected included relapse frequency, symptomatology, imaging findings, treatment regimens, peripheral blood profiles, EDSS scores, and MRI results. In addition, maternal drug concentrations, postpartum relapse rates, and neonatal development were monitored after delivery. Following the successful completion of the five-year follow-up, the research team plans to continue the prospective epidemiological study with ten-year follow-up phases. The aim of this study is to generate detailed clinical data on pregnancy-associated autoimmune diseases and to equip clinicians with evidence-based strategies for optimizing disease management during the reproductive age.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 28 Apr 2025
- Start date
- 21 Apr 2024
- Primary completion date
- Jan 2030
- Lead sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
- NCT number
- NCT07653984
What you commit to
- Study type: Observational
- Planned participants: 100
- From 21 Apr 2024 to the primary completion date, Jan 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals diagnosed with neuroimmune-related disorders.
Other
- Patient Group:
- Patients with an undetermined or unconfirmed diagnosis.
- Incomplete personal information that cannot be obtained through follow-up.
- Participants who voluntarily withdrew from the study and revoked informed consent.
- Healthy Control Group:
- Incomplete personal information that cannot be obtained through follow-up.
- Participants who voluntarily withdrew from the study and revoked informed consent.
Who the study is looking for
- Patient Group: A total of fifty participants are expected to be enrolled.
- Women aged 20-55 years with childbearing potential.
- Voluntary informed consent.
- Availability of complete personal information.
- A confirmed diagnosis of neuromyelitis optica spectrum disorder (NMOSD), multiple sclerosis (MS), autoimmune encephalitis, myasthenia gravis, Guillain-Barré syndrome, or myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
- Healthy Control Group: A total of fifty healthy women are expected to be included.
- Age- and sex-matched women of childbearing age with plans for pregnancy
- Voluntary informed consent.
- Availability of complete personal information.
Age in the registry: 20 years to 55 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Third Affiliated Hospital,Sun Yat-Sen University Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.