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Vitamin C Blood Levels and Spinal Fractures in People With Osteoporosis

Measures vitamin C in the blood of people with osteoporosis and spinal fractures.

Plain-language title generated from the registry record
Registry title: Link Between ASCorbemia Level and Osteoporosis

Key facts

Where
Nice, FranceSee the site

Where in France

  • CHU de NiceNice, FranceNo longer taking part

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Trial details

Who runs it
Centre Hospitalier Universitaire de Nice
Trial code
NCT07660484
Record updated
22 June 2026
Original description
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the RheumatologyRead full original descriptionShow less

ASCO Study: Link Between ASCorbemia Level and Osteoporosis

This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the Rheumatology

Inclusion: Men aged 50 yars or older ; Postmenopausal women ; Afilliated with a health insurance and system ; Written informed consent obtained; Group 1 : Clincal osteoporotic vertebral fracture confirmed by imaging within the previous month ; Followed in the Rheumatology department for management of vertebral fracture; Group 2 : Densitometric osteoporosis (T-score ≤ -2.5) ; No history of severe osteoporotic fracture ; No history of clinical or morphometric vertebral fracture.

Exclusion: Previous severe osteoporotic fracture for group B; infection, trauma or non osteoporotic causes ; Legal protection measure (guardianship, curatorship); inability to provide informed consent ; refusal to participate ; Vertebral fracture related to tumor,; asymptomatic vertebral fracture discovered incidentally ; Severe densitometric osteoporosis for group 2 .

ClinicalTrials.gov NCT07660484