Personalized Exercise Program for Young People Who Have Had Sarcoma
Tests a 12-week personalized exercise program in young people with sarcoma.
Plain-language title generated from the registry record
Registry title: Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
Key facts
- Where
- Boston, United StatesSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 15 and 39 years old?
Source: NCT07662239, who can take part
Where in United States
- Boston Children's HospitalBoston, United StatesTaking people
- Brigham and Women's HospitalBoston, United StatesTaking people
- Dana-Farber Cancer InstituteBoston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Dana-Farber Cancer Institute
- Trial code
- NCT07662239
- Record updated
- 26 August 2026
- Original description
This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma. The study will assess the feasibility of a standardized triage system for referring AYAs with sarcoma to appropriate exercise and rehabilitation services, and will also examine changes in physical function and health-related quality of life before and after a 12-week personalized exercise program.Read full original descriptionShow less
Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma. The study will assess the feasibility of a standardized triage system for referring AYAs with sarcoma to appropriate exercise and rehabilitation services, and will also examine changes in physical function and health-related quality of life before and after a 12-week personalized exercise program.
Inclusion: Diagnosed with a bone or soft tissue sarcoma; Age 15-39 at time of diagnosis; Age 15 and older at time of enrollment; Age 15-17 at time of enrollment, with assent from participant and consent from parent/legal guardian; Established patient of the DFCI Sarcoma Center or Jimmy Fund; Able to read and understand English (to complete required questionnaires and participate in training/coaching); Individuals who are not yet adults (teenagers) if they assent and their parents/legal guardians' consent to participation.
Exclusion: Currently participating in physical or occupational therapy; Unstable cardiovascular disease in the last 6 months; Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, untreated substance use disorder, severe personality disorder); Presence of medical conditions or medications that would prohibit participation in an exercise program; Pregnant; Meeting exercise guidelines of 150 minutes of moderate intensity/75 minutes of vigorous intensity physical activity per week plus consistent strength training (at least once per week) over the past 3 months. Assessed via Godin Leisure Time Questionnaire by study staff; Adults unable to consent.