Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis
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- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
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- Who runs it
- Tanta University
- Trial code
- NCT07664371
- Record updated
- 11 August 2026
- Original description
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.Read full original descriptionShow less
Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis: A Randomised Controlled Trial
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.
Inclusion: Adults with a clinical diagnosis of refractory knee OA who suffered from refractory knee pain (patients who had failed conservative medical and physical therapy for 6 months .
Exclusion: Patients with OA show improvement in pain after conservative medical and physical therapy; Patients evaluated by an orthopedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA; patients on anticoagulation therapy, who were not permitted to stop anticoagulation; Patients with allergies to local anesthetics; Patients with acute infections; Patients with implanted cardiac devices; Patients with knee tumors; Pregnant patients.