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Taking people in EgyptNo phase

Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis

Key facts

Where
Tanta, EgyptSee the site

Where in Egypt

  • Faculty of Medicine, Tanta UniversityTanta, EgyptContact: Aliaa Mamdouh Abdelaziz Farag, MDTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Tanta University
Trial code
NCT07664371
Record updated
11 August 2026
Original description
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.Read full original descriptionShow less

Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis: A Randomised Controlled Trial

The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.

Inclusion: Adults with a clinical diagnosis of refractory knee OA who suffered from refractory knee pain (patients who had failed conservative medical and physical therapy for 6 months .

Exclusion: Patients with OA show improvement in pain after conservative medical and physical therapy; Patients evaluated by an orthopedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA; patients on anticoagulation therapy, who were not permitted to stop anticoagulation; Patients with allergies to local anesthetics; Patients with acute infections; Patients with implanted cardiac devices; Patients with knee tumors; Pregnant patients.

ClinicalTrials.gov NCT07664371