Taking stroke patients straight to a combined scanner and angiography suite for clot removal
Tests whether a combined scan-and-treatment room speeds clot removal in adults with stroke.
Plain-language title generated from the registry record
Registry title: Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit
Key facts
- Where
- Beijing, ChinaSee the site
- Phase
- Phase 3
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18-60 with an acute ischemic stroke caused by a blocked brain artery, who can have a clot-removal procedure (thrombectomy) within 24 hours.
- Age
- 18 to 60 years
- Sex
- All sexes can join.
- Disease stage
- Acute ischemic stroke with a confirmed blocked brain artery (large vessel occlusion) that can be treated with endovascular intervention, seen on a CT scan with contrast given in a vein.
Main reasons for not taking part
- Known allergy to contrast agent
- Kidney function with GFR below 45 mL/min/1.73 m²
- Past kidney transplant
- Diabetes with current use of metformin
- Pregnant or breastfeeding women, or a positive pregnancy test at admission
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07670065, who can take part
Where in China
- Beijing Tiantan HospitalBeijing, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Beijing Tiantan Hospital
- Trial code
- NCT07670065
- Record updated
- 26 June 2026
- Original description
This study investigates whether direct transfer to an emergency stroke unit equipped with NeuAngio-CT reduces time to endovascular reperfusion in patients with acute ischemic stroke and suspected intracranial large-vessel occlusion.Those aged 18-60 years with acute ischemic stroke who are eligible for endovascular thrombectomy within 24 hours of symptom onset will be enrolled. Participants will be randomly assigned to one of two groups. In the intervention group, participants will undergo femoral or radial artery puncture, followed by intracranial and cervical CT angiography with intra-arterial contrast injection (iacCTA) performed using the sliding-rail NeuAngio-CT, and subsequent thrombectomy guided by fused CTA-DSA images. In the control group, participants will receive intracranial and cervical CT angiography with intra-venous contrast injection and the thrombectomy will guided by standard DSA imaging without use of the sliding-rail CT. The primary endpoint is puncture-to-successful-reperfusion time (PRT); if successful reperfusion is not achieved, the end-of-procedure time will be used.Read full original descriptionShow less
Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit to Reduce Time to Endovascular Reperfusion for Acute Ischemic Stroke
This study investigates whether direct transfer to an emergency stroke unit equipped with NeuAngio-CT reduces time to endovascular reperfusion in patients with acute ischemic stroke and suspected intracranial large-vessel occlusion.Those aged 18-60 years with acute ischemic stroke who are eligible for endovascular thrombectomy within 24 hours of symptom onset will be enrolled. Participants will be randomly assigned to one of two groups. In the intervention group, participants will undergo femoral or radial artery puncture, followed by intracranial and cervical CT angiography with intra-arterial contrast injection (iacCTA) performed using the sliding-rail NeuAngio-CT, and subsequent thrombectomy guided by fused CTA-DSA images. In the control group, participants will receive intracranial and cervical CT angiography with intra-venous contrast injection and the thrombectomy will guided by standard DSA imaging without use of the sliding-rail CT. The primary endpoint is puncture-to-successful-reperfusion time (PRT); if successful reperfusion is not achieved, the end-of-procedure time will be used.
Inclusion: Age 18-60 years; Clinical diagnosis of acute ischemic stroke eligible for immediate endovascular treatment; Time from symptom onset or last known well ≤ 24 hours; Intravenous intracranial and cervical CT angiography completed; Confirmed target vessel occlusion amenable to endovascular intervention based on intravenous intracranial and cervical CT angiography findings; Written informed consent obtained from the patient or their legally authorized representative.
Exclusion: Concomitant diabetes mellitus with current use of metformin; Known contrast agent allergy; History of kidney transplantation; Refractory hypertension (defined as systolic blood pressure ≥ 185 mmHg or diastolic blood pressure ≥ 110 mmHg) (Note: patients may be enrolled if blood pressure is successfully reduced and maintained at an acceptable level with antihypertensive therapy); Intracranial space-occupying lesion or other conditions deemed unsuitable for endovascular intervention on imaging; Renal insufficiency with GFR (glomerular filtration rate) < 45 mL/min/1.73 m²; Women who are pregnant, breastfeeding, or have a positive pregnancy test at admission; Any other serious comorbidity or complication that may interfere with study conduct or evaluation.