Studying kidney disease in children with inflammatory bowel disease
Looks at how often kidney disease occurs in children with bowel inflammation.
Plain-language title generated from the registry record
Registry title: Epidemiological Evaluation Of Chronic Kidney Disease In Pediatric Patients With Inflammatory Bowel Disease
Key facts
- Where
- Alessandria, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 2 and 17 years old?
Source: NCT07670988, who can take part
Where in Italy
- Pediatric UnitAlessandria, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
- Trial code
- NCT07670988
- Record updated
- 26 June 2026
- Original description
This multicenter observational cross-sectional study aims to evaluate the prevalence of chronic kidney disease (CKD) in pediatric patients with inflammatory bowel disease (IBD) and to compare it with a control group without IBD.Read full original descriptionShow less
A Multicenter, Cross-sectional Observational Study for the Epidemiological Evaluation of Chronic Kidney Disease in Pediatric Patients With Inflammatory Bowel Disease, and Its Relationship With Disease Activity and Medical Therapy.
This multicenter observational cross-sectional study aims to evaluate the prevalence of chronic kidney disease (CKD) in pediatric patients with inflammatory bowel disease (IBD) and to compare it with a control group without IBD.
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are chronic conditions that can also affect organs outside the intestine. Among these, kidney involvement has been reported, but data in pediatric populations are limited.
The study will collect clinical, laboratory, and demographic data from pediatric patients with IBD and matched controls without IBD. The main objective is to estimate the prevalence of CKD in children with IBD and compare it with that observed in the control group. Secondary objectives include describing patient characteristics and exploring potential associations between CKD, disease activity, and medical therapies.
The results of this study may improve the understanding of kidney complications in pediatric IBD and support earlier diagnosis and better clinical management.
Inclusion: Pediatric patients aged between 2 and 17 years; For the case group: confirmed diagnosis of inflammatory bowel disease according to Porto criteria; For the control group: absence of current or previous diagnosis of inflammatory bowel disease; Availability of clinical and laboratory data required for study evaluation; Written informed consent from parent or legal guardian, and assent from the minor when applicable.
Exclusion: History of pre-existing renal disease (congenital or acquired before IBD diagnosis); Presence of conditions that may affect renal function (e.g., diabetes mellitus, hypertension, chronic use of nephrotoxic drugs); Lack of informed consent.