Combined Muscle and Bone Measure in Adults Having Bone Density Scans
Tests a combined muscle and bone index in adults having bone density scans.
Plain-language title generated from the registry record
Registry title: Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study
Key facts
- Where
- Küçükçekmece, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who are going to have a routine bone density scan (DXA) at a rehabilitation outpatient clinic and who can do a handgrip strength test.
- Age
- 18 years or older
- Sex
- All sexes can join
- Biomarker or test result
- Lumbar spine and total hip bone density measurements that can be used for analysis
Main reasons for not taking part
- Secondary causes of osteoporosis (for example hyperparathyroidism, Cushing syndrome, cancer)
- History of metabolic bone disease
- Major trauma or fracture in the previous 6 months
- Arm or hand problems that affect handgrip strength testing (for example severe osteoarthritis, nerve disorders, major deformities)
- DXA scan that is not good enough for analysis
Read by machine on 9 November 2026.
Where in Türkiye
- Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, TurkeyKüçükçekmece, TürkiyeContact: Dilek Ün Oğuzhanasiltürk, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Kanuni Sultan Suleyman Training and Research Hospital
- Trial code
- NCT07677033
- Record updated
- 30 June 2026
- Original description
The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.Read full original descriptionShow less
Functional Muscle-Bone Incongruity Index (FKUI): Combined Evaluation of Handgrip Strength, Total Hip Bone Mineral Density, and Lumbar-Hip Bone Mineral Density Discordance in Adults Undergoing DXA
The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.
Inclusion: Age 18 years or older; Attendance at the Physical Medicine and Rehabilitation outpatient clinic; Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation; Ability to perform handgrip strength testing; Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis; Ability and willingness to provide written informed consent.
Exclusion: Major trauma or fracture within the previous 6 months; Secondary causes of osteoporosis (e.g., hyperparathyroidism, Cushing syndrome, malignancy, or other conditions affecting bone metabolism); History of metabolic bone disease; Upper extremity disorders that may significantly affect handgrip strength measurement (e.g., severe osteoarthritis, neurological disorders, major deformities); Age younger than 18 years; DXA measurements that are technically inadequate or unsuitable for analysis; Refusal or inability to provide written informed consent.