Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke
Key facts
- Where
- Berkeley, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07681102, who can take part
Where in United States
- Magnetic Tides Inc.Berkeley, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Magnetic Tides
- Trial code
- NCT07681102
- Record updated
- 6 July 2026
- Original description
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the feasibility and efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.Read full original descriptionShow less
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the feasibility and efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.
Inclusion: Adults aged 18-80 years who have a history of a unilateral stroke ≥ 12 m prior to enrollment; Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-55; Ability to communicate, understand, and give appropriate consent. Participants can follow two-step commands; Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive).
Exclusion: Botulinum toxin injections of the affected upper extremity within 3 months prior to onset of study assessments/testing through the last visit; Absolute contraindications related to non-invasive brain stimulation, including:; History of seizures in the last 12 months while taking anti-epilepsy medication Presence of any metal implants in the head (excluding the mouth), such as cortical stimulators and DBS, clips, coils, shunts, stents or skull plates, cochlear implants Permanent eye liner or head tattoos Implanted electronics such as pacemakers, defibrillators, intrathecal baclofen pumps or vagus nerve stimulator History of experiencing a serious adverse event during a previous transcranial magnetic stimulation (TMS) session; Participants with moderate or severe cognitive impairment (MoCA < 18); Language impairment or behavioral disorder that interferes with their ability to adhere to the protocol or to provide informed consent; Individuals who have a serious uncontrolled medical condition, including but not limited to severe cardiovascular and cardiopulmonary disease; Participants with sensory deficits FMA-S ≥ 6/12 (with proprioception ≥ 2/4); Pregnancy or plans to become pregnant during the study period; Severe spasticity of the affected upper limb (Modified Ashworth ≥ 3).