Nurse-led community clinics for uncontrolled high blood pressure in Monrovia, Liberia

Trial details

Who runs it

Johns Hopkins University

Trial code

NCT07681726

Record updated

8 September 2026

Original description

The goal of this study is to learn if a nurse-led, task-shifting, community-based program can help lower blood pressure in adults aged 25 and older with uncontrolled high blood pressure (hypertension) in Monrovia, Liberia. The program is delivered through community-based mobile clinics by community health nurses (CHNs) trained in WHO-aligned hypertension care within the Ministry of Health's (MOH) Community Health hypertension management protocols.Read full original descriptionShow less

Project HOPE (Hypertension Outreach Through Partnership and Engagement)

The goal of this study is to learn if a nurse-led, task-shifting, community-based program can help lower blood pressure in adults aged 25 and older with uncontrolled high blood pressure (hypertension) in Monrovia, Liberia. The program is delivered through community-based mobile clinics by community health nurses (CHNs) trained in WHO-aligned hypertension care within the Ministry of Health's (MOH) Community Health hypertension management protocols.

Participants will:

* Receive blood pressure treatment from trained community health nurses (CHNs) at community-based mobile clinics in their communities, including medication and lifestyle counseling. * Complete surveys at their first visit, at 4 to 6 weeks, and at 3 months about their experience, satisfaction, and medication use. * Attend follow-up visits at the mobile clinic based on their blood pressure levels.

Community health nurses delivering the program will complete structured training and be invited to complete surveys before and after training, and to take part in interviews about their experience at the end of the study.

The study will take place over 7 months in five high-thoroughfare communities in Monrovia, Liberia, and aims to enroll 150 participants.

Patient Participant Inclusion Criteria:; Adults aged ≥25 years; Stage 2 hypertension defined as either:; Systolic Blood Pressure (SBP) ≥160 mmHg at screening (Group A); OR; SBP 140-159 mmHg at screening with either documented elevation on more than one visit or a known history of hypertension (e.g., prior clinician diagnosis or current use of antihypertensive medication) (Group B); Patient Participant Exclusion Criteria:; <25 years of age; Hypertensive emergency with SBP ≥180 mmHg at screening (these patients will be referred to the nearest health center per local protocol; they may be re-screened for eligibility at a subsequent visit if SBP meets the inclusion criteria above); Diagnosis of end-stage renal disease (ESRD); Condition which interferes with outcome measurement (e.g., dialysis); Serious medical condition which either limits life expectancy or requires active management (e.g., certain cancers); Cognitive impairment or other condition preventing participation in the intervention; Active alcohol or substance use disorder (i.e., not sober/abstinent for ≥30 days), screened using the NIAAA Single Alcohol Screening Question; Pregnant or planning pregnancy in the next 24 months; Currently nursing a child; Current participation in another research study focused on reducing blood pressure; Current participation in a care management program related to health conditions (e.g., weight reduction, smoking cessation); Planning to move out of the geographic area within 7 months; Unwillingness to provide informed consent; Community Health Nurse (CHN) Participant Inclusion Criteria:; CHNs who were directly involved in delivering the nurse-led community-based hypertension intervention; Willing to provide oral informed consent for participation in pre/post-training surveys and semi-structured interviews; Community Health Nurse (CHN) Participant Exclusion Criteria:; CHNs who were not directly involved in the delivery of the intervention.

ClinicalTrials.gov NCT07681726