Pharmacist-led cholesterol management after acute coronary syndrome, guided by electronic health records
Tests a pharmacist-led program to lower LDL cholesterol in people with heart disease.
Plain-language title generated from the registry record
Registry title: Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study
Key facts
- Where
- Edmonton, CanadaSee the site
Where in Canada
- University of Alberta Hospital / Mazankowski Alberta Heart InstituteEdmonton, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Alberta
- Trial code
- NCT07685639
- Record updated
- 9 September 2026
- Original description
The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care.Read full original descriptionShow less
Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study
The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care.
The main question it aims to answer is:
• Does the EHR-LOCALE pathway increases the proportion of patients who reach the LDL-cholesterol target of <1.8 mmol/L at 6 months?
Participants in the interventional group receive:
* Pharmacist contact * Repeat lipid requisitions * Review of medications, adherence, and side effects * Treatment escalation according to national dyslipidemia guidelines
Inclusion: Adults over the age of 18; Resident of Alberta; Individuals hospitalized with an acute coronary syndrome and have undergone coronary angiography; Able to participate in follow-up contact if randomized to the intervention arm.
Exclusion: In-hospital mortality.