Personalized gamma sound stimulation to support thinking skills in healthy adults
Tests personalized gamma-frequency sound stimulation on thinking skills in 20 healthy adults.
Plain-language title generated from the registry record
Registry title: Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement
Key facts
- Where
- Taoyuan, TaiwanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 40 years old?
Source: NCT07690865, who can take part
Where in Taiwan
- Chang Gung UniversityTaoyuan, TaiwanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chang Gung Memorial Hospital
- Trial code
- NCT07690865
- Record updated
- 16 July 2026
- Original description
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization. While 40 Hz auditory stimulation has been widely studied, recent evidence suggests optimal frequencies vary by individual. Using a cross-over design with 20 healthy adults, the research compares "optimal" versus "non-optimal" frequencies over one-month intervention periods. Effectiveness is measured through EEG recordings and executive function tasks. The goal is to determine if personalized sensory intervention provides a more effective, non-invasive strategy for enhancing cognitive performance.Read full original descriptionShow less
Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement: An Intervention Study
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization. While 40 Hz auditory stimulation has been widely studied, recent evidence suggests optimal frequencies vary by individual. Using a cross-over design with 20 healthy adults, the research compares "optimal" versus "non-optimal" frequencies over one-month intervention periods. Effectiveness is measured through EEG recordings and executive function tasks. The goal is to determine if personalized sensory intervention provides a more effective, non-invasive strategy for enhancing cognitive performance.
Inclusion: Age between 18 to 40 years old; The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education; Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function; Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.); Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels; Auditory stimuli induce significant neural entrainment; Self-reported normal hearing.
Exclusion: Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.); Participants enrolled in any cognitive enhancement study within the past two months; Individuals with tinnitus or hyperacusis.