Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
Key facts
- Where
- Mānsehra, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 12 years old?
Source: NCT07694804, who can take part
Where in Pakistan
- Helping Hand Institute of rehabilitationMānsehra, PakistanContact: Dr. Pirzada Khattak HOD, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Ibadat International University, Islamabad
- Trial code
- NCT07694804
- Record updated
- 13 July 2026
- Original description
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities. Proprioceptive Neuromuscular Facilitation (PNF) and Task-Oriented Training (TOT) are commonly used rehabilitation approaches to improve motor function; however, evidence comparing their individual and combined effects on upper extremity function remains limited.Read full original descriptionShow less
Isolated Versus Combined Effects of Proprioceptive Neuromuscular Facilitation and Task-Oriented Training on Upper Extremity Function in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy often experience upper extremity impairments, including reduced coordination, muscle control, and functional hand use, which limit independence in daily activities. Proprioceptive Neuromuscular Facilitation (PNF) and Task-Oriented Training (TOT) are commonly used rehabilitation approaches to improve motor function; however, evidence comparing their individual and combined effects on upper extremity function remains limited.
This randomized controlled trial aims to compare the effects of PNF alone, TOT alone, and a combined PNF plus TOT intervention on upper extremity function in children with spastic diplegic cerebral palsy. Sixty-three children aged 6 to 12 years with Gross Motor Function Classification System (GMFCS) levels I to III will be randomly assigned to one of three intervention groups. Each group will receive supervised 45-minute treatment sessions, three times per week for six weeks.
Upper extremity function, functional independence, and joint range of motion will be assessed at baseline, mid-intervention (3 weeks), and post-intervention (6 weeks) using the Melbourne Assessment of Unilateral Upper Limb Function (MA2), Pediatric Evaluation of Disability Inventory-Functional Skills Scale (PEDI-FSS), and goniometric measurements. The findings of this study are expected to provide evidence regarding the most effective rehabilitation approach for improving upper extremity function in children with spastic diplegic cerebral palsy.
Inclusion: Children aged 6 to 12 years; Clinical diagnosis of spastic diplegic cerebral palsy; Gross Motor Function Classification System (GMFCS) Levels I-III; Ability to understand and follow simple verbal instructions; Medically stable and able to participate in physiotherapy sessions; Parent or legal guardian willing to provide written informed consent.
Exclusion: Orthopedic surgery involving the upper or lower extremities within the previous 6 months; Botulinum toxin injections administered within the previous 6 months; Uncontrolled epilepsy or other unstable neurological or medical conditions; Failure to obtain informed consent from a parent or legal guardian; Severe visual, hearing, or cognitive impairments that would interfere with assessment or treatment; Fixed upper extremity contractures or musculoskeletal deformities preventing participation in the intervention; Participation in another structured upper extremity rehabilitation program during the study period.