Comparing two bowel-cleansing drinks before colonoscopy for colorectal cancer screening
Compares two bowel-cleansing solutions, one with simethicone, in people having screening colonoscopy.
Plain-language title generated from the registry record
Registry title: Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy
Key facts
- Where
- Barcelona, SpainSee the site
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 50 to 69 who had a positive stool blood test in the colorectal cancer screening program and are booked for a screening colonoscopy at Hospital Clínic de Barcelona.
- Age
- 50 to 69 years
- Sex
- Men and women
- Earlier treatment
- Cannot have had a colonoscopy within the last year. Must have taken part in the colorectal cancer early detection program.
- Biomarker or test result
- Positive faecal occult blood test (≥20 μg Hb/g feces).
Main reasons for not taking part
- Severe kidney failure (grade IV or V) or severe heart failure (NYHA class III or IV)
- Colonoscopy within the last year
- Partial or total colon resection
- Personal history of colorectal cancer, ulcerative colitis, Crohn's disease or colorectal adenomas
- Pregnancy or breastfeeding
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 69 years old?
Source: NCT07696793, who can take part
Where in Spain
- Hospital Clinic de BarcelonaBarcelona, SpainContact: Maria PelliséTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Fundacion Clinic per a la Recerca Biomédica
- Trial code
- NCT07696793
- Record updated
- 10 July 2026
- Original description
Study to evaluate the efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy.Read full original descriptionShow less
Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy: a Randomized Parallel Comparative Trial CLEAN+
Study to evaluate the efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy.
Inclusion: Men and women aged 50 to 69; Have participated in the early detection program for colorectal cancer; Positive result in the fecal occult blood test (≥20 μg Hb/g feces); Scheduled screening colonoscopy at Hospital Clínic de Barcelona; Signed informed consent form.
Exclusion: Partial or total colon resection; Severe renal failure (grade IV or V) (Annex 6, Stages of Renal Impairment) and/or congestive heart failure (New York Heart Association Scale Class III and IV) (Annex 7, NYHA Scale); Mental disability or severe mental disorder (schizophrenia and other psychotic disorders, recurrent severe major depressive disorders, severe obsessive-compulsive disorder, severe personality disorders, and bipolar disorders); Personal history of CRC or colorectal pathology that requires specific follow-up (ulcerative colitis, Crohn's disease, or colorectal adenomas); Terminal illness or serious illness/disability that contraindicates subsequent colon study; Gastrointestinal disorders that contraindicate the use of study products (gastric emptying disorders, gastrointestinal perforation or obstruction, ileus, toxic megacolon); Hypersensitivity to the active ingredients of excipients; Glucose-6-phosphate dehydrogenase deficiency; Colonoscopy within the last year; Barthel Index of <20 (Annex 5, Barthel Index) and who also meet the Rome IV Criteria for the diagnosis of functional constipation (Annex 8, Rome IV Criteria); Do not understand spoken or written Catalan or Spanish; Hypermagnesemia; Rhabdomyolysis; Phenylketonuria; Pregnancy or breastfeeding.