Dressing change schedules for PICC lines in colon or pancreatic cancer
Compares weekly and every-14-day PICC dressing changes in adults with cancer.
Plain-language title generated from the registry record
Registry title: Frequency of Care for Peripherally Inserted Central Vascular Access In the Prevention of Marsi
Key facts
- Where
- Badalona, SpainSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with colon or pancreas cancer who need a PICC line (a thin tube placed in an arm vein) for chemotherapy. It compares dressing changes every week with every 14 days.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Colon cancer or pancreas cancer
- Earlier treatment
- Needs a PICC line for chemotherapy with FOLFOX6, FOLFOX4, FOLFIRI, or mFOLFIRI
Main reasons for not taking part
- Catheter-related infection within the previous 30 days
- Known allergy to adhesive dressings
- Raynaud syndrome
- Skin jaundice or cyanosis at baseline
Read by machine on 9 November 2026.
Where in Spain
- Sandra Cabrera JaimeBadalona, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Institut Català d'Oncologia
- Trial code
- NCT07697170
- Record updated
- 13 July 2026
- Original description
This randomized controlled clinical trial evaluates the safety equivalence between weekly and biweekly dressing changes for peripherally inserted central catheters (PICC) in oncology patients receiving outpatient chemotherapy.Read full original descriptionShow less
Frequency of Care for Peripherally Inserted Central Vascular Access In the Prevention of Marsi: A Randomized Clinical Trial
This randomized controlled clinical trial evaluates the safety equivalence between weekly and biweekly dressing changes for peripherally inserted central catheters (PICC) in oncology patients receiving outpatient chemotherapy.
The study will assess vascular access functionality, skin integrity including Medical Adhesive-Related Skin Injury (MARSI), and the incidence of catheter-related complications.
A total of 150 adult patients with colon or pancreas cancer receiving chemotherapy and requiring PICC insertion will be randomized into two groups: weekly dressing changes (control group) or biweekly dressing changes every 14 days (intervention group).
Participants will be followed during chemotherapy treatment for a minimum of six cycles and up to twelve sessions. Outcomes include catheter-related complications, patient satisfaction with vascular access care, and quality of life measured using the EORTC QLQ-C30 questionnaire (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire).
Inclusion: Age ≥18 years; Diagnosis of colon or pancreas cancer; Indication for PICC insertion for chemotherapy administration; Chemotherapy regimen including FOLFOX6, FOLFOX4, FOLFIRI, or mFOLFIRI; Ability to understand the study procedures; Signed written informed consent.
Exclusion: Catheter-related infection within the previous 30 days; Known allergy to adhesive dressings; Raynaud syndrome; Skin jaundice or cyanosis at baseline.