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Two Types of Exercise and Gut Bacteria in People With Fatty Liver Disease

Compares two exercise styles and their effect on gut bacteria in fatty liver.

Plain-language title generated from the registry record
Registry title: High-intensity Interval Training Versus Moderate Intensity Continuous Training on Gut Microbiota in Non-alcoholic Fatty Liver

Key facts

Where
Cairo, EgyptSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 60 years old?

Source: NCT07697313, who can take part

Where in Egypt

  • out-patient clinic, faculty of physical therapy, Horus universityCairo, EgyptNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Horus University
Trial code
NCT07697313
Record updated
13 July 2026
Original description
To compare High-Intensity Interval Training versus moderate intensity continuous training on gut microbiota in Non- Alcoholic Fatty Liver.Read full original descriptionShow less

High-intensity Interval Training Versus Moderate Intensity Continuous Training on Gut Microbiota in Non-alcoholic Fatty Liver

To compare High-Intensity Interval Training versus moderate intensity continuous training on gut microbiota in Non- Alcoholic Fatty Liver.

Inclusion: Patients from both genders aged 40 - 60 years old diagnosed with Non-alcoholic Fatty Liver disease by ultrasonography; Body mass index will range from 30 to 34.9 kg/m²; Patients with central obesity (waist circumference 90 cm for men and 85 cm for women); Patients who have taken no regular exercise in the last year (<3 times/week and 30 min/time; No antibiotic or probiotic use for at least last 3 months; Medical drugs such as metformin, sulfonylureas, statins, and blood pressure medication were eligible, as well as stable.

Exclusion: Use of medications affecting gut microbiota (e.g., laxatives, metformin, proton pump inhibitors); History of liver cirrhosis or other chronic liver diseases; Recent gastrointestinal infections or surgeries; Diabetes Mellitus type 1 or uncontrolled type 2; Cardiovascular, respiratory, or musculoskeletal disorders limiting exercise capacity; Uncontrolled hypertension; Communication disorders; Bleeding disorders; Active smokers; Pregnancy or breastfeeding.

ClinicalTrials.gov NCT07697313