Studying lung health in Batswana adults with and without HIV
Observes lung function and possible causes of lung disease in adults with and without HIV.
Plain-language title generated from the registry record
Registry title: Lung Health and the Microbiome Among Adults in Botswana: the Go-hema Cohort
Key facts
- Where
- Gaborone, BotswanaSee the site
Where in Botswana
- Local Health Facilities in GaboroneGaborone, BotswanaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Duke University
- Trial code
- NCT07699614
- Record updated
- 13 July 2026
- Original description
Chronic respiratory diseases like chronic obstructive pulmonary disease (COPD) are responsible for millions of deaths each year, the majority of which occur in low- and middle-income countries (LMICs). LMICs also have high rates of abnormal lung function, including restrictive spirometric pattern (RSP), which can precede the development of chronic respiratory diseases and is associated with all-cause mortality. Additionally, LMICs in sub-Saharan Africa are home to the majority of the world's population of people with HIV (PWH). HIV increases the risk of COPD and COPD associated mortality, but the mechanisms underlying this risk are incompletely understood.Read full original descriptionShow less
Determinants of Lung Health Among Batswana Adults With and Without HIV: the Go-Hema Study
Chronic respiratory diseases like chronic obstructive pulmonary disease (COPD) are responsible for millions of deaths each year, the majority of which occur in low- and middle-income countries (LMICs). LMICs also have high rates of abnormal lung function, including restrictive spirometric pattern (RSP), which can precede the development of chronic respiratory diseases and is associated with all-cause mortality. Additionally, LMICs in sub-Saharan Africa are home to the majority of the world's population of people with HIV (PWH). HIV increases the risk of COPD and COPD associated mortality, but the mechanisms underlying this risk are incompletely understood.
Inclusion: Adults 35 years of age or older; In case at a clinic in Botswana; Documented HIV status; Ability to provide informed consent.
Exclusion: Respiratory infection in the prior 4 weeks; Thoracic surgery or myocardial infarction in the prior 6 weeks; Active pulmonary tuberculosis; Inability to perform spirometry including eye, abdominal, or; Pregnancy.