Light therapy and vein harvesting methods for wound healing after heart bypass surgery
Tests light therapy on leg wound healing in adults having coronary bypass surgery.
Plain-language title generated from the registry record
Registry title: Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
Key facts
- Where
- São Paulo, BrazilSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07699679, who can take part
Where in Brazil
- Hospital São Paulo, Federal University of São PauloSão Paulo, BrazilNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Federal University of São Paulo
- Trial code
- NCT07699679
- Record updated
- 7 October 2026
- Original description
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with sham laser, conventional harvesting with photobiomodulation, no-touch harvesting with sham laser, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.Read full original descriptionShow less
Impact of Photobiomodulation in Coronary Artery Bypass Surgery: Comparison Between No-Touch and Conventional Saphenous Vein Harvesting Techniques on Clinical Outcomes, Functional Capacity, and Wound Healing: A Randomized Clinical Trial
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with sham laser, conventional harvesting with photobiomodulation, no-touch harvesting with sham laser, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.
Inclusion: Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG); Use of the saphenous vein as a graft for myocardial revascularization; Ability to understand the study procedures and provide written informed consent.
Exclusion: Emergency coronary artery bypass surgery; Previous surgery in the lower limb that prevents saphenous vein harvesting; Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy; Active infection at the surgical site or lower limb; Severe peripheral arterial disease in the lower limbs; Hemodynamic instability preventing study protocol procedures; Participation in another interventional clinical trial that may interfere with the outcomes of this study; Patients unable to perform postoperative functional capacity assessments.