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Registry of Lung and Chest Cancers Occurring During Pregnancy

Collects information on people with lung or chest cancer who are expecting a child.

Plain-language title generated from the registry record
Registry title: LUCINAE Registry: Thoracic Cancers During Pregnancy

Key facts

Where
Baden, Bellinzona, Geneva, and Winterthur, SwitzerlandSee the 4 sites

Where in Switzerland

  • Kantonsspital BadenBaden, SwitzerlandTaking people
  • Istituto Oncologico della Svizzera Italiana (IOSI)Bellinzona, SwitzerlandTaking people
  • Geneva University Hospital (HUG)Geneva, SwitzerlandTaking people
  • Kantonsspital WinterthurWinterthur, SwitzerlandTaking people

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  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Oncology Institute of Southern Switzerland
Trial code
NCT07699861
Record updated
21 October 2026
Original description
The LUCINAE Registry is an international, multicenter observational study collecting data on patients with thoracic cancers (including lung cancer) who are expecting a child. This includes women diagnosed during pregnancy, women who become pregnant during or after cancer, and men receiving cancer treatment at the time their partner conceives.Read full original descriptionShow less

LUCINAE: LUng and Thoracic Cancers In pregNAncy rEgistry

The LUCINAE Registry is an international, multicenter observational study collecting data on patients with thoracic cancers (including lung cancer) who are expecting a child. This includes women diagnosed during pregnancy, women who become pregnant during or after cancer, and men receiving cancer treatment at the time their partner conceives.

Because thoracic cancers during pregnancy are rare, there is limited information to guide clinical decisions. This registry aims to describe patient characteristics, diagnostic approaches, treatments, and maternal and fetal outcomes. Data are collected retrospectively and prospectively from participating centers.

The results of this registry are expected to improve understanding of thoracic cancers in this setting and support the development of future clinical recommendations.

Inclusion: 1. All patients with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities) and pregnancy (positive pregnancy test) including:; Patients receiving a diagnosis of thoracic cancer during pregnancy; Patients who became pregnant while having active thoracic cancer; Patients previously treated for a thoracic cancer and becoming pregnant in the 5 years following end of treatment OR Men with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities), who were undergoing active oncological treatment at the time their partner conceived their child; 2. Available information about pregnancy outcomes; 3. Age ≥ 18 years.

Exclusion: 1. Patient missing data about thoracic cancer stage and diagnosis; 2. For retrospective patients, documented refusal to the use of clinical data for research purposes.

ClinicalTrials.gov NCT07699861