Comparing in-person and home-based exercise programs for people waiting for a kidney transplant
Compares supervised and remote exercise, nutrition and support programs in adults awaiting kidney transplant.
Plain-language title generated from the registry record
Registry title: Remote vs In-Person Prehabilitation for Kidney Transplant Candidates
Key facts
- Where
- Barcelona, SpainSee the site
Where in Spain
- Hospital Clinic BarcelonaBarcelona, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital Clinic of Barcelona
- Trial code
- NCT07701382
- Record updated
- 14 July 2026
- Original description
Patients with advanced chronic kidney disease awaiting deceased-donor kidney transplantation frequently experience progressive functional decline, frailty, reduced mobility, and poor quality of life while on the transplant waiting list. Although multimodal prehabilitation programs based on exercise, nutritional optimization, and psychological support have shown promising benefits in major surgery, their implementation in kidney transplant candidates remains limited due to barriers related to accessibility, fatigue, transportation, and treatment burden.Read full original descriptionShow less
Implementation of a Multimodal Prehabilitation Program for Patients With Advanced Chronic Kidney Disease Awaiting Deceased-Donor Kidney Transplantation: A Comparison of In-Person and Remote Delivery Models
Patients with advanced chronic kidney disease awaiting deceased-donor kidney transplantation frequently experience progressive functional decline, frailty, reduced mobility, and poor quality of life while on the transplant waiting list. Although multimodal prehabilitation programs based on exercise, nutritional optimization, and psychological support have shown promising benefits in major surgery, their implementation in kidney transplant candidates remains limited due to barriers related to accessibility, fatigue, transportation, and treatment burden.
This randomized single-center clinical trial aims to evaluate the feasibility, adherence, and effectiveness of a multimodal prehabilitation program in patients awaiting deceased-donor kidney transplantation, comparing an in-person supervised model with a remote home-based model supported by a digital platform. The primary outcome will be the change in functional capacity measured by the 6-Minute Walk Test (6MWT). Secondary outcomes include physical activity level, frailty, nutritional status, kidney disease-specific quality of life (KDQOL-36), postoperative recovery quality (QoR-15), postoperative complications, and program adherence.
The study seeks to generate clinically applicable evidence regarding the implementation and scalability of remote prehabilitation strategies in patients with advanced chronic kidney disease, with the potential to improve accessibility, sustainability, and perioperative outcomes in kidney transplantation.
Inclusion: Adults aged 18 years or older; Patients with advanced chronic kidney disease on the waiting list for deceased-donor kidney transplantation; Ability to perform moderate-intensity physical exercise; Able and willing to provide written informed consent.
Exclusion: Severe cognitive impairment limiting participation in the intervention or assessments; Active infection at the time of enrollment; Clinically unstable medical condition; Absolute contraindication to physical exercise; Physical or musculoskeletal limitations preventing participation in the exercise program.