Whether feedback on treatment helps heart failure care follow guidelines
Looks at whether feedback improves guideline-based treatment in adults with heart failure.
Plain-language title generated from the registry record
Registry title: Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF)
Key facts
- Where
- Rotterdam, NetherlandsSee the site
Where in Netherlands
- Erasmus University Medical CentreRotterdam, NetherlandsTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Jasper Brugts MD PhD
- Trial code
- NCT07702760
- Record updated
- 13 October 2026
- Original description
The IMPLEMENT HF study is part of the national heart failure quality of care registry (evaluation of given health care). Within the HF registry, the investigators will investigate whether mirror information on the actual 4 pillars of guideline directed medical therapy (GDMT) in HFrEF patients will help to further improve the implementation of GDMT.Read full original descriptionShow less
Guideline Implementation and Quality of Care Evaluation in Patients With Heart Failure and Reduced Ejection Fraction (HFrEF): The IMPLEMENT-HF Study.
The IMPLEMENT HF study is part of the national heart failure quality of care registry (evaluation of given health care). Within the HF registry, the investigators will investigate whether mirror information on the actual 4 pillars of guideline directed medical therapy (GDMT) in HFrEF patients will help to further improve the implementation of GDMT.
Data will be used from the national HF registry in the Netherlands. Two groups will be studied, one where the HCP receives the mirror information on GDMT and one where both the patient and the HCP receive the mirror information on GDMT. GDMT or the 4 pillars treatment is standard of care as recommended by the ESC HF guidelines, indicated for all HFrEF patients. The project is a quality of care registry and health care evaluation to optimize adherence to the HF guidelines.
Inclusion: Written informed consent; Age ≥18 years; Diagnosis of HFrEF according to ESC HF 2026 guidelines (EF <50%); Participant is willing to participate for 1 years of follow-up for standard of care at the outpatient clinic of the participating hospital and the local investigator follows the patients for the time frame of 1 years on reported endpoints.
Exclusion: A major CV event (e.g. disabling stroke, open heart surgery) within 3 months of enrollment, if likely to interfere with GDMT titration or regular follow-up; Advanced or Endstage Heart Failure stage in which advanced HF treatment with an LVAD or heart transplant is anticipated within 6 months after the baseline visit; At enrollment the patient has an established diagnosis of heart failure with reduction ejection fraction; An expected life expectancy less than 1 year due to other comorbidities according to the treating physician.