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Measuring Energy Needs and Feeding After Pancreas Surgery

Studies how much energy and food patients need after pancreas tumor surgery.

Plain-language title generated from the registry record
Registry title: Energy Expenditure and Nutrition After Pancreatic Surgery

Key facts

Where
Athens, GreeceSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults 18 to 75 who are scheduled for partial or total pancreas surgery because of a pancreatic tumor. It measures how much energy they burn after surgery.

Age
18 to 75 years
Sex
All sexes can join.
Disease stage
A pancreatic tumor, with total or partial pancreatectomy planned (including the Whipple procedure or distal pancreatectomy).
Earlier treatment
People already on enteral nutrition before surgery, or unable to eat by mouth before surgery, cannot join.

Main reasons for not taking part

  • Under 18 or over 75 years old
  • Pregnancy
  • Cannot tolerate the calorimetry canopy or mask long enough for a valid measurement
  • Already on enteral nutrition before surgery, or cannot eat by mouth before surgery
  • Unable or unwilling to give informed consent

Read by machine on 9 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Source: NCT07703813, who can take part

Where in Greece

  • Evaggelismos General HospitalAthens, GreeceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Evangelismos Hospital
Trial code
NCT07703813
Record updated
14 July 2026
Original description
This prospective observational cohort study examines the energy requirements and nutritional care of patients undergoing total or partial pancreatectomy for pancreatic tumors. Patients undergoing pancreatectomy face major metabolic stress, a high burden of preoperative malnutrition, and frequent exocrine or endocrine insufficiency, yet procedure-specific nutritional guidance is limited. The study measures resting energy expenditure (REE) directly by indirect calorimetry during the early postoperative period and compares it with widely used predictive equations (Harris-Benedict, Schofield) and simplified weight-based targets (25 and 30 kcal/kg) to determine how accurately clinicians can estimate energy needs when calorimetry is unavailable. In the same patients, the study records the route of postoperative nutrition (enteral, parenteral, or combined), energy and protein intake relative to requirements, and diet-related symptoms, and follows postoperative complications, hospital readmission, mortality, and changes in body weight and body mass index through 3-6 months after surgery. By capturing measured energy expenditure and nutritional delivery in one cohort, the study aims to clarify whether adequacy of energy and protein intake, feeding route, or both influence recovery, and to provide primary data for developing individualized nutritional support protocols in this high-risk surgical population.Read full original descriptionShow less

Resting Energy Expenditure, Nutritional Intake, and Postoperative Outcomes in Patients Undergoing Total or Partial Pancreatectomy for Pancreatic Tumors: A Prospective Observational Cohort Study

This prospective observational cohort study examines the energy requirements and nutritional care of patients undergoing total or partial pancreatectomy for pancreatic tumors. Patients undergoing pancreatectomy face major metabolic stress, a high burden of preoperative malnutrition, and frequent exocrine or endocrine insufficiency, yet procedure-specific nutritional guidance is limited. The study measures resting energy expenditure (REE) directly by indirect calorimetry during the early postoperative period and compares it with widely used predictive equations (Harris-Benedict, Schofield) and simplified weight-based targets (25 and 30 kcal/kg) to determine how accurately clinicians can estimate energy needs when calorimetry is unavailable. In the same patients, the study records the route of postoperative nutrition (enteral, parenteral, or combined), energy and protein intake relative to requirements, and diet-related symptoms, and follows postoperative complications, hospital readmission, mortality, and changes in body weight and body mass index through 3-6 months after surgery. By capturing measured energy expenditure and nutritional delivery in one cohort, the study aims to clarify whether adequacy of energy and protein intake, feeding route, or both influence recovery, and to provide primary data for developing individualized nutritional support protocols in this high-risk surgical population.

Inclusion: Age 18 years or older; Scheduled to undergo total or partial pancreatectomy (including pancreaticoduodenectomy/Whipple procedure or distal pancreatectomy) for a pancreatic tumor; Able to complete indirect calorimetry measurement by canopy or face mask for the required duration; Able to provide written informed consent.

Exclusion: Age under 18 years, greater than 75 years; Pregnancy; Inability to tolerate the calorimetry canopy or mask for the duration required for a valid measurement; Unable or unwilling to provide informed consent; patients already on preoperative enteral nutrition or unable to feed orally preoperatively.

ClinicalTrials.gov NCT07703813