Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI
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- Are you between 18 and 80 years old?
Source: NCT07704268, who can take part
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Contact the study team: see the registry record → Contacts and Locations
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- Who runs it
- Shengjing Hospital
- Trial code
- NCT07704268
- Record updated
- 10 November 2026
- Original description
This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder contractions) and related voiding dysfunctions in patients with spinal cord injury. The main questions it seeks to answer are:Read full original descriptionShow less
A Randomized, Double-Blind, Sham-Controlled Trial of Sacral Nerve Root High-Frequency Magnetic Stimulation Combined With Ultrasound Therapy for Detrusor Overactivity in Patients With Spinal Cord Injury
This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder contractions) and related voiding dysfunctions in patients with spinal cord injury. The main questions it seeks to answer are:
What is the effect of high-frequency sacral nerve root magnetic stimulation on detrusor overactivity and bladder function in patients with spinal cord injury?
What is the effect of bladder-directed ultrasound therapy on detrusor overactivity and bladder wall compliance in patients with spinal cord injury?
Is the combination of these two treatment modalities superior to magnetic stimulation alone?
Inclusion: Diagnosis of spinal cord injury (SCI) above the sacral level according to the International Standards for Neurological Classification of Spinal Cord Injury (revised 2011), confirmed by CT or MRI; Detrusor overactivity confirmed by urodynamic study; No severe urinary system diseases such as tumors, stones, infection, or organic urinary tract obstruction; No severe hepatic/renal insufficiency, pulmonary, or cardiovascular diseases; Aged 18-80 years; Able to understand and comply with the required examinations, rehabilitation assessments, and treatment, and provide written informed consent.
Exclusion: Presence of metallic implants within 10 cm of the magnetic stimulation treatment area; Unstable vital signs or critically ill condition; Any other diseases or conditions that may interfere with the study outcomes; Severe autonomic dysreflexia.