More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
Key facts
- Where
- Erlangen, GermanySee the site
Where in Germany
- Department of Pediatrics and Adolescent MedicineErlangen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Erlangen-Nürnberg Medical School
- Trial code
- NCT07705178
- Record updated
- 30 October 2026
- Original description
In this study, we investigate the cardiopulmonary health of survivors who underwent cancer treatment for acute lymphoblastic leukemia (ALL) or lymphoma during childhood, compared with healthy controls. Modern imaging techniques (MRI, MSOT, and echocardiography) as well as questionnaires assessing cardiopulmonary and mental health are used.Read full original descriptionShow less
"MaximALL" More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
In this study, we investigate the cardiopulmonary health of survivors who underwent cancer treatment for acute lymphoblastic leukemia (ALL) or lymphoma during childhood, compared with healthy controls. Modern imaging techniques (MRI, MSOT, and echocardiography) as well as questionnaires assessing cardiopulmonary and mental health are used.
Inclusion: no cancer diagnosis; no lung diseases; no vascular diseases; No subjective reduction in physical performance; age >/= 18 years; Completed therapy for ALL; age >/= 3 years; Completed therapy for lymphoma; age >/= 3 years.
Exclusion: Previous lung surgery; Previous lung surgery; Previous lung surgery; Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure); General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.); Survivors of ALL:; Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure); General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.); Survivors of Lymphoma:; Critical condition (requiring respiratory support, ventilation, oxygen, shock, symptomatic heart failure); General contraindications for MRI examinations (e.g. electrical implants such as cardiac pacemakers or perfusion pumps, copper IUD etc.); Pregnancy, Lactation; Known pleural or pericardial effusion; Marked thoracic deformities/malformations; Injuries that do not allow physical stress diagnostics; Rejection of MRI imaging; Pregnancy, Lactation; Known pleural or pericardial effusion; Marked thoracic deformities/malformations; Injuries that do not allow physical stress diagnostics; Rejection of MRI imaging; Pregnancy, Lactation; Known pleural or pericardial effusion; Marked thoracic deformities/malformations; Injuries that do not allow physical stress diagnostics; Rejection of MRI imaging.
Control Group:.