Insomnia and Post-Dental Surgery Pain: A Prospective Study
Key facts
- Where
- Roma, ItalySee the site
Where in Italy
- Clinica Odontoiatrica; Fondazione Universitaria Policlinico A.Gemelli IRCCSRoma, ItalyContact: Patrizia Gallenzi, Prof, DDSTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Trial code
- NCT07712432
- Record updated
- 3 September 2026
- Original description
The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures. Recent scientific literature highlights a bidirectional relationship between sleep disorders and pain in dentistry, suggesting that disturbed sleep may actively exacerbate subsequent pain perception. Although postoperative pain, swelling, and masticatory difficulties are common after dental extractions, clinical data investigating the direct impact of preoperative sleep quality on these surgical outcomes remain scarce. This study will enroll adult patients undergoing routine dental extractions and allocate them into two cohorts based on their baseline sleep quality: patients without preoperative sleep disturbances and patients with preoperative sleep disturbances. Pain levels and sleep parameters will be assessed using validated questionnaires before the surgery and at a 7-day follow-up. The primary objective is to determine whether the presence of preoperative insomnia leads to a significant increase in perceived postoperative surgical pain.Read full original descriptionShow less
Effect of Insomnia on Post-operative Dental Surgical Pain: a Prospective Observational Study in an Adult Population.
The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures. Recent scientific literature highlights a bidirectional relationship between sleep disorders and pain in dentistry, suggesting that disturbed sleep may actively exacerbate subsequent pain perception. Although postoperative pain, swelling, and masticatory difficulties are common after dental extractions, clinical data investigating the direct impact of preoperative sleep quality on these surgical outcomes remain scarce. This study will enroll adult patients undergoing routine dental extractions and allocate them into two cohorts based on their baseline sleep quality: patients without preoperative sleep disturbances and patients with preoperative sleep disturbances. Pain levels and sleep parameters will be assessed using validated questionnaires before the surgery and at a 7-day follow-up. The primary objective is to determine whether the presence of preoperative insomnia leads to a significant increase in perceived postoperative surgical pain.
Inclusion: Age over or egual 18 years; Need for odontoiatric surgical intervention (dental extractions); Willingness to participate in the study by completing the proposed questionnaires; Good understanding of the Italian language; Ability to understand and sign the informed consent form.
Exclusion: Pharmacological therapy interfering with sleep or pain at the time of recruitment; Acute pain or ongoing infections at the time of recruitment; Relevant comorbidities; Pregnancy; Impossibility to complete the follow-up.