Fractional CO2 laser plus corticosteroid cream for psoriasis of the palms and soles
Compares laser plus corticosteroid cream with cream alone in adults with palm and sole psoriasis.
Plain-language title generated from the registry record
Registry title: Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis
Key facts
- Where
- Cairo, EgyptSee the site
- Phase
- Phase 4
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07713212, who can take part
Where in Egypt
- Cairo UniversityCairo, EgyptNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Cairo University
- Trial code
- NCT07713212
- Record updated
- 20 July 2026
- Original description
To assess whether adding fractional laser to topical corticosteroid improves treatment outcomes in palmoplanter psoriasis compared to topical corticosteroid alone.Read full original descriptionShow less
Comparative Study of the Efficacy and Safety of Combined Fractional CO₂ Laser and Topical Corticosteroid Versus Topical Corticosteroid Only in the Treatment of Palmoplantar Psoriasis: A Pilot Randomized Controlled Clinical Trial
To assess whether adding fractional laser to topical corticosteroid improves treatment outcomes in palmoplanter psoriasis compared to topical corticosteroid alone.
Inclusion: Adults aged ≥18 years; Stable psoriasis; Confirmed cases of palmoplantar psoriasis (with or without psoriasis elsewhere) dermoscopically(Hand _held dermoscopy) and histopathologically if required; Willingness to comply with treatment and follow-up; Written informed consent obtained.
Exclusion: Use of:; Systemic antipsoriatic therapy within 3 months; Biologic therapy within 12 weeks; Topical treatment on palms/soles within 2 weeks; History of photosensitivity disorders; Other palmoplantar dermatoses (eczema, tinea, keratoderma); Generlized Pustular psoriasis; Erythrodermic psoriasis; Pregnancy or lactation.